AADE 14

ORLANDO – Here’s something to consider when prescribing insulin therapy for patients with type 2 diabetes: psychological insulin resistance.

After conducting a dozen focus groups at the University of Pittsburgh Diabetes Institute, researchers found that the condition is alive and well among patients with type 2 diabetes, mostly because of misunderstanding and lack of information about available injection tools.

Credit: © BakiBG / ThinkStockPhotos.com

But the condition has a simple cure: Either take the time to educate the patient about insulin therapy and various injection options or refer the patient to a diabetes educator.

"We need to recognize how to effectively educate patients," said Robert Powell at the annual meeting of the American Association of Diabetes Educators. "Demonstrate. Talk about side effects and dosing. Ask patients their concerns and provide them with options. Always seek out that teachable moment."

Patients’ resistance arises from negative beliefs about diabetes and insulin therapy, fear of injection, or fear of "what others may think of them if they see them injecting themselves," said Mr. Powell, diabetes educator and program manager at the University of Pittsburgh Diabetes Institute. Sometimes, patients think that insulin therapy is a sign that they’ve failed in managing their diabetes, he said.

A recent study found that "The acceptance of insulin is very low in type 2 diabetes patients. The option to inhale insulin increases the acceptability for some but not the majority of patients," the authors wrote. (Diabetes Technol. Ther. 2013;15:703-11).

Physicians, too, are sometimes reluctant to prescribe insulin, "because they know their patients have PIR [psychological insulin resistance], and this leads to clinical inertia," said Mr. Powell.

PIR is complex and multifaceted, according to a 2009 review published in the journal Quality of Life Research (2009;18:23-32).

PIR "plays an important, although often ignored, role in diabetes management," the authors wrote. "By tailoring treatments to patients’ PIR, clinicians may be better able to help their patients begin insulin treatment sooner and improve compliance, thus facilitating target glycemic control."

To further explore the patients’ perceptions and reactions to insulin therapy delivery modes, Mr. Powell and his colleagues conducted 12 patient focus groups – 100 patients in total. Six focus groups included patients who were insulin naive, and the other six had patients who had been taking insulin. The sessions were led by trained moderators and certified diabetes educators.

Patients were in their 50s, nearly half were white, and they had had diabetes for an average of 12-15 years.

Results showed that the majority of participants saw insulin therapy as negative and a sign of failure. They questioned the long-term prognosis and cited side effects and contraindications for insulin therapy.

Patients made comments such as "I think the drug itself is like cancer. You know, the chemotherapy kills, and I think the insulin does more harm than good," or "I feel like I was kind of a failure in doing my part and taking care of myself."

When patients were presented with various injection options, they requested more information, but cost was the main barrier to device selection and acceptance of insulin therapy, Mr. Powell reported.

Many preferred pens over vials and smaller needles over larger ones. Some patients said, "Why didn’t my doctor give me those needles [pointing to smaller ones]. I would prefer the smaller needle."

Many patients said that they weren’t shown insulin supplies and devices that are currently available. They weren’t shown how, when, and where to inject. Some said they were referred to the pharmacy for that information. Some said "Someone in the medical field needs to show me the correct way."

On the other hand, a patient who received proper instructions said, "I was lucky. My doctor sent me to an educator. They actually sat down and would not leave until I learned ... I also got information on insulin and injecting."

When the providers were interviewed for the study, they reported that patients had fear of needles; many said that they didn’t know about various needle options, and some cited lack of time to provide patients with appropriate diabetes education.

"Onsite training is something we have to make sure happens. To do so, we need to convince providers to refer patients to diabetes educators," said Mr. Powell. To reduce PIR, "we need provider-to-provider interaction," he said, encouraging diabetes educators to reach out to providers and ask for referrals.

"It’s our job to take the initiative to bridge the gap in diabetes education," he said.

Mr. Powell had no financial disclosures.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Here’s something to consider when prescribing insulin therapy for patients with type 2 diabetes: psychological insulin resistance.

After conducting a dozen focus groups at the University of Pittsburgh Diabetes Institute, researchers found that the condition is alive and well among patients with type 2 diabetes, mostly because of misunderstanding and lack of information about available injection tools.

Credit: © BakiBG / ThinkStockPhotos.com

But the condition has a simple cure: Either take the time to educate the patient about insulin therapy and various injection options or refer the patient to a diabetes educator.

"We need to recognize how to effectively educate patients," said Robert Powell at the annual meeting of the American Association of Diabetes Educators. "Demonstrate. Talk about side effects and dosing. Ask patients their concerns and provide them with options. Always seek out that teachable moment."

Patients’ resistance arises from negative beliefs about diabetes and insulin therapy, fear of injection, or fear of "what others may think of them if they see them injecting themselves," said Mr. Powell, diabetes educator and program manager at the University of Pittsburgh Diabetes Institute. Sometimes, patients think that insulin therapy is a sign that they’ve failed in managing their diabetes, he said.

A recent study found that "The acceptance of insulin is very low in type 2 diabetes patients. The option to inhale insulin increases the acceptability for some but not the majority of patients," the authors wrote. (Diabetes Technol. Ther. 2013;15:703-11).

Physicians, too, are sometimes reluctant to prescribe insulin, "because they know their patients have PIR [psychological insulin resistance], and this leads to clinical inertia," said Mr. Powell.

PIR is complex and multifaceted, according to a 2009 review published in the journal Quality of Life Research (2009;18:23-32).

PIR "plays an important, although often ignored, role in diabetes management," the authors wrote. "By tailoring treatments to patients’ PIR, clinicians may be better able to help their patients begin insulin treatment sooner and improve compliance, thus facilitating target glycemic control."

To further explore the patients’ perceptions and reactions to insulin therapy delivery modes, Mr. Powell and his colleagues conducted 12 patient focus groups – 100 patients in total. Six focus groups included patients who were insulin naive, and the other six had patients who had been taking insulin. The sessions were led by trained moderators and certified diabetes educators.

Patients were in their 50s, nearly half were white, and they had had diabetes for an average of 12-15 years.

Results showed that the majority of participants saw insulin therapy as negative and a sign of failure. They questioned the long-term prognosis and cited side effects and contraindications for insulin therapy.

Patients made comments such as "I think the drug itself is like cancer. You know, the chemotherapy kills, and I think the insulin does more harm than good," or "I feel like I was kind of a failure in doing my part and taking care of myself."

When patients were presented with various injection options, they requested more information, but cost was the main barrier to device selection and acceptance of insulin therapy, Mr. Powell reported.

Many preferred pens over vials and smaller needles over larger ones. Some patients said, "Why didn’t my doctor give me those needles [pointing to smaller ones]. I would prefer the smaller needle."

Many patients said that they weren’t shown insulin supplies and devices that are currently available. They weren’t shown how, when, and where to inject. Some said they were referred to the pharmacy for that information. Some said "Someone in the medical field needs to show me the correct way."

On the other hand, a patient who received proper instructions said, "I was lucky. My doctor sent me to an educator. They actually sat down and would not leave until I learned ... I also got information on insulin and injecting."

When the providers were interviewed for the study, they reported that patients had fear of needles; many said that they didn’t know about various needle options, and some cited lack of time to provide patients with appropriate diabetes education.

"Onsite training is something we have to make sure happens. To do so, we need to convince providers to refer patients to diabetes educators," said Mr. Powell. To reduce PIR, "we need provider-to-provider interaction," he said, encouraging diabetes educators to reach out to providers and ask for referrals.

"It’s our job to take the initiative to bridge the gap in diabetes education," he said.

Mr. Powell had no financial disclosures.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Here’s something to consider when prescribing insulin therapy for patients with type 2 diabetes: psychological insulin resistance.

After conducting a dozen focus groups at the University of Pittsburgh Diabetes Institute, researchers found that the condition is alive and well among patients with type 2 diabetes, mostly because of misunderstanding and lack of information about available injection tools.

Credit: © BakiBG / ThinkStockPhotos.com

But the condition has a simple cure: Either take the time to educate the patient about insulin therapy and various injection options or refer the patient to a diabetes educator.

"We need to recognize how to effectively educate patients," said Robert Powell at the annual meeting of the American Association of Diabetes Educators. "Demonstrate. Talk about side effects and dosing. Ask patients their concerns and provide them with options. Always seek out that teachable moment."

Patients’ resistance arises from negative beliefs about diabetes and insulin therapy, fear of injection, or fear of "what others may think of them if they see them injecting themselves," said Mr. Powell, diabetes educator and program manager at the University of Pittsburgh Diabetes Institute. Sometimes, patients think that insulin therapy is a sign that they’ve failed in managing their diabetes, he said.

A recent study found that "The acceptance of insulin is very low in type 2 diabetes patients. The option to inhale insulin increases the acceptability for some but not the majority of patients," the authors wrote. (Diabetes Technol. Ther. 2013;15:703-11).

Physicians, too, are sometimes reluctant to prescribe insulin, "because they know their patients have PIR [psychological insulin resistance], and this leads to clinical inertia," said Mr. Powell.

PIR is complex and multifaceted, according to a 2009 review published in the journal Quality of Life Research (2009;18:23-32).

PIR "plays an important, although often ignored, role in diabetes management," the authors wrote. "By tailoring treatments to patients’ PIR, clinicians may be better able to help their patients begin insulin treatment sooner and improve compliance, thus facilitating target glycemic control."

To further explore the patients’ perceptions and reactions to insulin therapy delivery modes, Mr. Powell and his colleagues conducted 12 patient focus groups – 100 patients in total. Six focus groups included patients who were insulin naive, and the other six had patients who had been taking insulin. The sessions were led by trained moderators and certified diabetes educators.

Patients were in their 50s, nearly half were white, and they had had diabetes for an average of 12-15 years.

Results showed that the majority of participants saw insulin therapy as negative and a sign of failure. They questioned the long-term prognosis and cited side effects and contraindications for insulin therapy.

Patients made comments such as "I think the drug itself is like cancer. You know, the chemotherapy kills, and I think the insulin does more harm than good," or "I feel like I was kind of a failure in doing my part and taking care of myself."

When patients were presented with various injection options, they requested more information, but cost was the main barrier to device selection and acceptance of insulin therapy, Mr. Powell reported.

Many preferred pens over vials and smaller needles over larger ones. Some patients said, "Why didn’t my doctor give me those needles [pointing to smaller ones]. I would prefer the smaller needle."

Many patients said that they weren’t shown insulin supplies and devices that are currently available. They weren’t shown how, when, and where to inject. Some said they were referred to the pharmacy for that information. Some said "Someone in the medical field needs to show me the correct way."

On the other hand, a patient who received proper instructions said, "I was lucky. My doctor sent me to an educator. They actually sat down and would not leave until I learned ... I also got information on insulin and injecting."

When the providers were interviewed for the study, they reported that patients had fear of needles; many said that they didn’t know about various needle options, and some cited lack of time to provide patients with appropriate diabetes education.

"Onsite training is something we have to make sure happens. To do so, we need to convince providers to refer patients to diabetes educators," said Mr. Powell. To reduce PIR, "we need provider-to-provider interaction," he said, encouraging diabetes educators to reach out to providers and ask for referrals.

"It’s our job to take the initiative to bridge the gap in diabetes education," he said.

Mr. Powell had no financial disclosures.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Older hospitalized patients with diabetes who felt unprepared for discharge or who had coping difficulties after discharge had a significantly increased risk of readmission within 30 days in a prospective mixed-methods study.

The findings have important implications for diabetes educators, according to Jacqueline LaManna, Ph.D., of the University of Central Florida, Orlando.

Of 96 patients with a mean age of 75 years who were included in the qualitative and quantitative study, 30 experienced an event of recidivism, defined as an unplanned provider or emergency department visit, and 16 of those were readmitted within 30 days, Dr. LaManna reported at the annual meeting of the American Association of Diabetes Educators.

Perceived readiness for discharge was lower in those who experienced an event of 30-day recidivism. Other factors associated with 30-day recidivism included difficulty managing medications, difficulty controlling or managing diabetes, and difficulty managing other chronic health problems. All these associations were statistically significant and were interrelated, Dr. LaManna said.

Difficulty managing medications after discharge was also associated with lower perceptions of transition quality.

Scores on the 15-item Care Transition Measure (CTM-15) – a measure of perceived transition quality – were positively correlated, with high statistical significance, with readiness for discharge, quality of discharge content provided, and skill of the nurse in delivering discharge content. Greater reported difficulty in the early transition period was associated with lower CTM-15 scores.

Scores on the Post-Discharge Coping Difficulties Scale (PDCDS) were higher in subjects who reported unmet information needs, those who experienced 30-day recidivism, and those who experienced problems managing medications, controlling diabetes, and managing other chronic illness during the early and intermediate transition periods.

A model including three factors that were significant predictors of recidivism – 7-day PDCDS score, 30-day PDCDS score, and difficulty managing chronic illness – correctly classified 78% of cases of event recidivism within 30 days, Dr. LaManna said.

Factors that were not associated with recidivism – either in the early (within 7 days) or intermediate (within 30 days) stage after discharge – included age and sex, chronic disease dyad pattern, diabetes-related health status variables, use of hospitalist services, length of stay, quality of discharge teaching, availability of an in-home family care provider, and use of home health services.

Several major themes, with implications for diabetes educators, emerged from the following findings, Dr. LaManna said:

• The daily stuff is difficult. Study participants commonly reported having difficulty with personal care and household tasks, walking and mobility, transportation, and obtaining supplies and medicine.

• Engineering care at home is complex. Many participants reported feeling that they "come last," because they are the caretakers for grandchildren, elderly spouses, and/or elderly parents. Managing things on their own is also difficult, and while they were diligent in mobilizing resources for support in an effort to remain independent, support systems are very fragile. Also, the hospital-to-home transition is difficult on families and this increases patient stress.

• Life is stressful. Many subjects complained about having to deal with too many outside influences with respect to their care and decisions, and many struggled with grief and depression and/or anxiety and frustration.

• Managing numerous complex health problems is onerous. Maintaining diabetes control was difficult for many patients, as was managing other chronic health problems. Trying to keep track of multiple medications was a particular challenge, and many subjects said they needed more information to help them with self-management.

Of note, many of these factors were at least as much of an issue at 30 days as they were at 7 days. For example, personal care remained an issue over time, with an equal proportion (56%) of patients reporting have such difficulties at 7 and 30 days, respectively. Further, the overall percentage of patients reporting difficulty managing multiple health problems increased from 52% to 78%, and the percentage having difficulty controlling their diabetes, in particular, increased from 18% to 29%.

This latter finding is particularly concerning given that the cut-off for most case management programs is 30 days.

"They are setting up for the next [recidivism] event," Dr. La Manna said.

The findings show that the home recovery transition is dynamic, and that the needs of older adults and family caregivers change.

Adults with cognitive impairment were not included in this study, so the findings represent somewhat of a "best-case scenario."

Thus, the findings suggest that even in "ideal" cases, the transition may be difficult, Dr. LaManna said, noting that the obstacles patients face are numerous.

"We need to be considering, as diabetes educators, what’s going on – not just with diabetes, but with other chronic health conditions. Multimorbidity is a really important thing," Dr. LaManna said.

The findings also suggest a need for inclusion of discharge readiness assessment into transitional care practices to improve predischarge identification of patients at risk for recidivism, and a need for sequential postdischarge follow-up for a longer period of time.

In the ambulatory setting, it would be useful to include PDCDS assessment, which includes only 10 simple questions.

"It might help you to identify somebody who’s struggling at home who could benefit from referral right then and there – at least warranting some follow-up. That could absolutely very easily be done in ambulatory setting," she said, noting that inclusion of a family stress assessment into transition planning is also important.

The findings suggest that diabetes educators have the potential to positively affect the transition experiences of hospitalized older adults and their family caregivers (the hospital from which patients for this study were recruited had no diabetes educators on staff).

Dr. LaManna reported having no disclosures.

ORLANDO – Older hospitalized patients with diabetes who felt unprepared for discharge or who had coping difficulties after discharge had a significantly increased risk of readmission within 30 days in a prospective mixed-methods study.

The findings have important implications for diabetes educators, according to Jacqueline LaManna, Ph.D., of the University of Central Florida, Orlando.

Of 96 patients with a mean age of 75 years who were included in the qualitative and quantitative study, 30 experienced an event of recidivism, defined as an unplanned provider or emergency department visit, and 16 of those were readmitted within 30 days, Dr. LaManna reported at the annual meeting of the American Association of Diabetes Educators.

Perceived readiness for discharge was lower in those who experienced an event of 30-day recidivism. Other factors associated with 30-day recidivism included difficulty managing medications, difficulty controlling or managing diabetes, and difficulty managing other chronic health problems. All these associations were statistically significant and were interrelated, Dr. LaManna said.

Difficulty managing medications after discharge was also associated with lower perceptions of transition quality.

Scores on the 15-item Care Transition Measure (CTM-15) – a measure of perceived transition quality – were positively correlated, with high statistical significance, with readiness for discharge, quality of discharge content provided, and skill of the nurse in delivering discharge content. Greater reported difficulty in the early transition period was associated with lower CTM-15 scores.

Scores on the Post-Discharge Coping Difficulties Scale (PDCDS) were higher in subjects who reported unmet information needs, those who experienced 30-day recidivism, and those who experienced problems managing medications, controlling diabetes, and managing other chronic illness during the early and intermediate transition periods.

A model including three factors that were significant predictors of recidivism – 7-day PDCDS score, 30-day PDCDS score, and difficulty managing chronic illness – correctly classified 78% of cases of event recidivism within 30 days, Dr. LaManna said.

Factors that were not associated with recidivism – either in the early (within 7 days) or intermediate (within 30 days) stage after discharge – included age and sex, chronic disease dyad pattern, diabetes-related health status variables, use of hospitalist services, length of stay, quality of discharge teaching, availability of an in-home family care provider, and use of home health services.

Several major themes, with implications for diabetes educators, emerged from the following findings, Dr. LaManna said:

• The daily stuff is difficult. Study participants commonly reported having difficulty with personal care and household tasks, walking and mobility, transportation, and obtaining supplies and medicine.

• Engineering care at home is complex. Many participants reported feeling that they "come last," because they are the caretakers for grandchildren, elderly spouses, and/or elderly parents. Managing things on their own is also difficult, and while they were diligent in mobilizing resources for support in an effort to remain independent, support systems are very fragile. Also, the hospital-to-home transition is difficult on families and this increases patient stress.

• Life is stressful. Many subjects complained about having to deal with too many outside influences with respect to their care and decisions, and many struggled with grief and depression and/or anxiety and frustration.

• Managing numerous complex health problems is onerous. Maintaining diabetes control was difficult for many patients, as was managing other chronic health problems. Trying to keep track of multiple medications was a particular challenge, and many subjects said they needed more information to help them with self-management.

Of note, many of these factors were at least as much of an issue at 30 days as they were at 7 days. For example, personal care remained an issue over time, with an equal proportion (56%) of patients reporting have such difficulties at 7 and 30 days, respectively. Further, the overall percentage of patients reporting difficulty managing multiple health problems increased from 52% to 78%, and the percentage having difficulty controlling their diabetes, in particular, increased from 18% to 29%.

This latter finding is particularly concerning given that the cut-off for most case management programs is 30 days.

"They are setting up for the next [recidivism] event," Dr. La Manna said.

The findings show that the home recovery transition is dynamic, and that the needs of older adults and family caregivers change.

Adults with cognitive impairment were not included in this study, so the findings represent somewhat of a "best-case scenario."

Thus, the findings suggest that even in "ideal" cases, the transition may be difficult, Dr. LaManna said, noting that the obstacles patients face are numerous.

"We need to be considering, as diabetes educators, what’s going on – not just with diabetes, but with other chronic health conditions. Multimorbidity is a really important thing," Dr. LaManna said.

The findings also suggest a need for inclusion of discharge readiness assessment into transitional care practices to improve predischarge identification of patients at risk for recidivism, and a need for sequential postdischarge follow-up for a longer period of time.

In the ambulatory setting, it would be useful to include PDCDS assessment, which includes only 10 simple questions.

"It might help you to identify somebody who’s struggling at home who could benefit from referral right then and there – at least warranting some follow-up. That could absolutely very easily be done in ambulatory setting," she said, noting that inclusion of a family stress assessment into transition planning is also important.

The findings suggest that diabetes educators have the potential to positively affect the transition experiences of hospitalized older adults and their family caregivers (the hospital from which patients for this study were recruited had no diabetes educators on staff).

Dr. LaManna reported having no disclosures.

ORLANDO – Older hospitalized patients with diabetes who felt unprepared for discharge or who had coping difficulties after discharge had a significantly increased risk of readmission within 30 days in a prospective mixed-methods study.

The findings have important implications for diabetes educators, according to Jacqueline LaManna, Ph.D., of the University of Central Florida, Orlando.

Of 96 patients with a mean age of 75 years who were included in the qualitative and quantitative study, 30 experienced an event of recidivism, defined as an unplanned provider or emergency department visit, and 16 of those were readmitted within 30 days, Dr. LaManna reported at the annual meeting of the American Association of Diabetes Educators.

Perceived readiness for discharge was lower in those who experienced an event of 30-day recidivism. Other factors associated with 30-day recidivism included difficulty managing medications, difficulty controlling or managing diabetes, and difficulty managing other chronic health problems. All these associations were statistically significant and were interrelated, Dr. LaManna said.

Difficulty managing medications after discharge was also associated with lower perceptions of transition quality.

Scores on the 15-item Care Transition Measure (CTM-15) – a measure of perceived transition quality – were positively correlated, with high statistical significance, with readiness for discharge, quality of discharge content provided, and skill of the nurse in delivering discharge content. Greater reported difficulty in the early transition period was associated with lower CTM-15 scores.

Scores on the Post-Discharge Coping Difficulties Scale (PDCDS) were higher in subjects who reported unmet information needs, those who experienced 30-day recidivism, and those who experienced problems managing medications, controlling diabetes, and managing other chronic illness during the early and intermediate transition periods.

A model including three factors that were significant predictors of recidivism – 7-day PDCDS score, 30-day PDCDS score, and difficulty managing chronic illness – correctly classified 78% of cases of event recidivism within 30 days, Dr. LaManna said.

Factors that were not associated with recidivism – either in the early (within 7 days) or intermediate (within 30 days) stage after discharge – included age and sex, chronic disease dyad pattern, diabetes-related health status variables, use of hospitalist services, length of stay, quality of discharge teaching, availability of an in-home family care provider, and use of home health services.

Several major themes, with implications for diabetes educators, emerged from the following findings, Dr. LaManna said:

• The daily stuff is difficult. Study participants commonly reported having difficulty with personal care and household tasks, walking and mobility, transportation, and obtaining supplies and medicine.

• Engineering care at home is complex. Many participants reported feeling that they "come last," because they are the caretakers for grandchildren, elderly spouses, and/or elderly parents. Managing things on their own is also difficult, and while they were diligent in mobilizing resources for support in an effort to remain independent, support systems are very fragile. Also, the hospital-to-home transition is difficult on families and this increases patient stress.

• Life is stressful. Many subjects complained about having to deal with too many outside influences with respect to their care and decisions, and many struggled with grief and depression and/or anxiety and frustration.

• Managing numerous complex health problems is onerous. Maintaining diabetes control was difficult for many patients, as was managing other chronic health problems. Trying to keep track of multiple medications was a particular challenge, and many subjects said they needed more information to help them with self-management.

Of note, many of these factors were at least as much of an issue at 30 days as they were at 7 days. For example, personal care remained an issue over time, with an equal proportion (56%) of patients reporting have such difficulties at 7 and 30 days, respectively. Further, the overall percentage of patients reporting difficulty managing multiple health problems increased from 52% to 78%, and the percentage having difficulty controlling their diabetes, in particular, increased from 18% to 29%.

This latter finding is particularly concerning given that the cut-off for most case management programs is 30 days.

"They are setting up for the next [recidivism] event," Dr. La Manna said.

The findings show that the home recovery transition is dynamic, and that the needs of older adults and family caregivers change.

Adults with cognitive impairment were not included in this study, so the findings represent somewhat of a "best-case scenario."

Thus, the findings suggest that even in "ideal" cases, the transition may be difficult, Dr. LaManna said, noting that the obstacles patients face are numerous.

"We need to be considering, as diabetes educators, what’s going on – not just with diabetes, but with other chronic health conditions. Multimorbidity is a really important thing," Dr. LaManna said.

The findings also suggest a need for inclusion of discharge readiness assessment into transitional care practices to improve predischarge identification of patients at risk for recidivism, and a need for sequential postdischarge follow-up for a longer period of time.

In the ambulatory setting, it would be useful to include PDCDS assessment, which includes only 10 simple questions.

"It might help you to identify somebody who’s struggling at home who could benefit from referral right then and there – at least warranting some follow-up. That could absolutely very easily be done in ambulatory setting," she said, noting that inclusion of a family stress assessment into transition planning is also important.

The findings suggest that diabetes educators have the potential to positively affect the transition experiences of hospitalized older adults and their family caregivers (the hospital from which patients for this study were recruited had no diabetes educators on staff).

Dr. LaManna reported having no disclosures.

ORLANDO – A new protocol for managing mild diabetic ketoacidosis in the emergency department led to a substantially improved discharge rate at a large teaching hospital.

Prior to development of the Emergency Valuable Approach and Diabetes Education (EVADE) protocol, almost all patients who presented with diabetic ketoacidosis (DKA) were admitted to the hospital, and most of those were admitted to the intensive care unit. However, in the most recent month for which outcomes data for the EVADE protocol are available, 24 of 106 patients (23%) managed according to the protocol were discharged from the ED and 82 were admitted, Marianne Chojnicki, a registered nurse and certified diabetes educator at the Joslin Diabetes Center, Boston, reported at the annual meeting of the American Association of Diabetes Educators.

The average length of stay in the ED for those who were discharged was 20 hours. The average length of stay in the hospital for 23 patients with a non-ICU admission was 136 hours, and the average length of stay in the ICU for 59 patients with an ICU admission was 33 hours, followed by 77 hours in the hospital after ICU discharge.

The findings have important implications for the care of patients presenting with DKA, which is documented in up to 9% of all hospital discharge summaries among patients with diabetes, and which is associated with mortality of up to 2%, Ms. Chojnicki noted.

"That’s a significant number of lives that are lost each year from a preventable event," she said.

In an effort to improve the discharge rate to at least 10%, Joslin Diabetes Center physicians, nurses, and diabetes educators worked together with Beth Israel Deaconess Medical Center in Boston to develop the EVADE protocol, which stemmed from a clinical approach used to manage DKA, and which is initiated in the ED based on clinical triggers.

They thought that a significant number of admissions were avoidable in a well-managed, coordinated system. The goal was to provide optimal cost-effective management for DKA, Ms. Chojnicki said.

From the outset, diabetes education was recognized as a key component of this protocol, she noted.

The education is individualized and covers multiple topics, such as identification of the circumstances leading up to DKA, a review of insulin action and technique of administration, and a review of ways to prevent DKA recurrence.

Evaluating the EVADE protocol

To evaluate the effectiveness of the protocol, a system was put in place to identify all patients who presented to the ED with blood glucose higher than 300 mg/dL and bicarbonate of 20 mEq/L or less. The patients were flagged for enrollment to be managed according to the EVADE protocol if their status was determined to be caused by DKA, and if they consented.

This process began in September 2013, and the first several months were spent refining management and defining quality indicators.

Month 8 results suggest that the protocol is effective for increasing discharge rates and reducing ICU admissions.

"Our initial goal was to discharge 10%, so we are above goal," Ms. Chojnicki said.

Overall, patients with mild to moderate DKA are going home from the ED, she said.

Typically, those with moderate DKA are admitted if they have a secondary diagnosis, and those patients are going to non-ICU beds.

"Only the sickest of the sick – basically those who are acidotic – are the patients going to the ICU," she said.

Preliminary data from an ongoing review of the results by a health economist show that despite the fact that the sickest patients are going to the ICU, the number of ICU days is decreasing in the wake of the EVADE protocol implementation.

This seems counterintuitive, but the latest data show that before EVADE, the average time spent in the ICU was 47.8 hours, and after EVADE the average time spent in the ICU was 31.6 hours.

"We shaved off 16.2 hours in one of the highest-cost areas of the hospital," Ms. Chojnicki said.

Notably, only one patient who was treated according to the EVADE protocol returned to the ED within 30 days, and that was a patient with issues related to alcohol abuse, she noted.

The findings suggest that mild DKA can be optimally managed in the setting of identification of the triggering factor, stabilization of glucose and electrolyte imbalances, patient education, and close follow-up, and that such management allows for more patients to be discharged from the ED, she said.

Ms. Chojnicki reported having no disclosures.

The EVADE protocol, step by step

The EVADE protocol for eligible patients begins with initiation of intravenous fluids but withholding insulin until initial labs are available. Once lab results confirm diabetic ketoacidosis, the staff initiates IV insulin.

A team including an attending endocrinologist, two nurse practitioners, and a certified diabetes educator are alerted when a patient is enrolled into the protocol.

Patients with all forms of DKA, including mild DKA without an anion gap, are managed on insulin drip with an endpoint goal of reaching a bicarbonate level of 21 mEq/L.

"The decision [to keep the patient in the ED for further observation and treatment or admit to the ICU] is based on the severity of the DKA and/or existing concurrent medical illness. If admitted to the ICU, the patient remains in the ICU arm of the DKA protocol, which involves frequent monitoring of glucose, electrolytes, venous blood gas, and urine output. Treatment is aimed at correcting the DKA and associated electrolyte disturbances," explained Maria Koen, a nurse practitioner and certified diabetes educator at Joslin Diabetes Center.

Regardless of whether the patient is admitted or remains in the ED, treatment involves the same IV insulin algorithm, which calls for no initial bolus; the starting rate is based on the initial finger stick, Ms. Koen noted.

Other features of the protocol include hourly finger sticks with adjustment of the dose with a goal of a target blood glucose of 100-180 mg/dL. Every 3 hours, someone on the team assesses venous blood gas and electrolytes.

IV fluid is run concurrently with IV insulin. Once the glucose drops to less than 250 mg/dL, fluid is changed to 5% dextrose in normal saline (D5NS). Once glucose increases again to 250 mg/dL, the protocol calls for discontinuation of D5NS with continuation of IV insulin infusion until the acidosis resolves.

If severe hypoglycemia occurs, D50 (50% dextrose) can be given as a bolus to reach the target of 100-180 mg/dL. The insulin drip is then resumed at 50% of the rate prior to the hypoglycemic event.

"Generally, we use normal saline or lactated Ringer’s as a first choice for IV fluid, at a rate of approximately 1 liter an hour for the first 4 hours, and this may be adjusted for patients who are at risk for volume overload, such as elders or patients with chronic kidney disease or congestive heart failure," she said.

After the first 4 hours, the IV solution may be changed to half of the normal saline, or half of the D5, if blood glucose drops below 250 mg/dL, at a rate of 125-250 cc per hour.

IV fluids may also be discontinued at this point if the patient is able to tolerate oral fluids.

The protocol also calls for electrolyte repletion as needed. Potassium may be added to each liter of IV fluid if the serum potassium reaches less than 5 mEq/L and the patient is voiding. The amount added is at the discretion of the attending physician, Ms. Koen said.

"Keep in mind that as the acidosis resolves, serum potassium will decrease. In such events, if severe hypokalemia occurs, it may be necessary to either decrease the insulin rate or temporarily hold the IV insulin drip," she said, noting that oral potassium and IV or oral phosphate can also be given once a patient can tolerate oral intake.

Insulin pumps should be removed to avoid overlap with the IV insulin, and the team should assess pump function and self-management.

Urine output and ability to tolerate oral intake should be assessed throughout the protocol, and patients should eat as soon as they are able to tolerate oral intake. The team should assess clinical status every 4 hours.

The patients’ care can move beyond the strictures of the protocol once they are either admitted to the ICU or stabilized in the ED. Those not admitted to the ICU can be discharged to home once their anion gap closes, their bicarbonate reaches more than 20 mEq/L, they can tolerate oral intake, and they successfully transition to a subcutaneous insulin regimen.

The transition to subcutaneous insulin requires that the basal dose be determined based on the patient’s home long-acting insulin dose or adjusted based on the nurse practitioner’s or doctor’s recommendations. Dosing for patients who are newly diagnosed or insulin naïve is calculated based on body weight in kilograms x 0.2.

When the patient is able to tolerate oral intake, prandial subcutaneous insulin based on the home prandial insulin dose should be initiated. Dosing in those who are insulin naïve should be based on body weight in kilograms x 0.2 and divided by 3 (but only with team recommendation).

"When transitioning from the IV insulin drip to subcutaneous insulin, if only basal insulin is given we recommend an overlap of the IV insulin drip for 2 hours. If both basal and prandial insulin are given at the same time, the recommendation is to overlap the insulin drip for at least 1 hour, and then the drip may be turned off," Ms. Koen said.

Insulin pumps may be restarted under the guidance of the certified diabetes educator. Electrolytes and glucose should be reassessed 2 hours after the insulin drip is stopped to ensure there is no return of the DKA.

Any patients with pH below 7.3, bicarbonate below 21 mEq/L, or an inability to tolerate oral intake will remain in the ED for continued observation and management. The patient is ready for discharge once pH is greater than 7.3, the anion gap closes, glucose reaches 250 mg/dL, and the patient can tolerate oral intake and has transitioned to subcutaneous insulin.

Following discharge, someone on the team should phone the patient, ideally within 24 hours, to ensure compliance with the postdischarge plan and schedule a follow-up clinic visit.

Ms. Koen reported having no disclosures.

ORLANDO – A new protocol for managing mild diabetic ketoacidosis in the emergency department led to a substantially improved discharge rate at a large teaching hospital.

Prior to development of the Emergency Valuable Approach and Diabetes Education (EVADE) protocol, almost all patients who presented with diabetic ketoacidosis (DKA) were admitted to the hospital, and most of those were admitted to the intensive care unit. However, in the most recent month for which outcomes data for the EVADE protocol are available, 24 of 106 patients (23%) managed according to the protocol were discharged from the ED and 82 were admitted, Marianne Chojnicki, a registered nurse and certified diabetes educator at the Joslin Diabetes Center, Boston, reported at the annual meeting of the American Association of Diabetes Educators.

The average length of stay in the ED for those who were discharged was 20 hours. The average length of stay in the hospital for 23 patients with a non-ICU admission was 136 hours, and the average length of stay in the ICU for 59 patients with an ICU admission was 33 hours, followed by 77 hours in the hospital after ICU discharge.

The findings have important implications for the care of patients presenting with DKA, which is documented in up to 9% of all hospital discharge summaries among patients with diabetes, and which is associated with mortality of up to 2%, Ms. Chojnicki noted.

"That’s a significant number of lives that are lost each year from a preventable event," she said.

In an effort to improve the discharge rate to at least 10%, Joslin Diabetes Center physicians, nurses, and diabetes educators worked together with Beth Israel Deaconess Medical Center in Boston to develop the EVADE protocol, which stemmed from a clinical approach used to manage DKA, and which is initiated in the ED based on clinical triggers.

They thought that a significant number of admissions were avoidable in a well-managed, coordinated system. The goal was to provide optimal cost-effective management for DKA, Ms. Chojnicki said.

From the outset, diabetes education was recognized as a key component of this protocol, she noted.

The education is individualized and covers multiple topics, such as identification of the circumstances leading up to DKA, a review of insulin action and technique of administration, and a review of ways to prevent DKA recurrence.

Evaluating the EVADE protocol

To evaluate the effectiveness of the protocol, a system was put in place to identify all patients who presented to the ED with blood glucose higher than 300 mg/dL and bicarbonate of 20 mEq/L or less. The patients were flagged for enrollment to be managed according to the EVADE protocol if their status was determined to be caused by DKA, and if they consented.

This process began in September 2013, and the first several months were spent refining management and defining quality indicators.

Month 8 results suggest that the protocol is effective for increasing discharge rates and reducing ICU admissions.

"Our initial goal was to discharge 10%, so we are above goal," Ms. Chojnicki said.

Overall, patients with mild to moderate DKA are going home from the ED, she said.

Typically, those with moderate DKA are admitted if they have a secondary diagnosis, and those patients are going to non-ICU beds.

"Only the sickest of the sick – basically those who are acidotic – are the patients going to the ICU," she said.

Preliminary data from an ongoing review of the results by a health economist show that despite the fact that the sickest patients are going to the ICU, the number of ICU days is decreasing in the wake of the EVADE protocol implementation.

This seems counterintuitive, but the latest data show that before EVADE, the average time spent in the ICU was 47.8 hours, and after EVADE the average time spent in the ICU was 31.6 hours.

"We shaved off 16.2 hours in one of the highest-cost areas of the hospital," Ms. Chojnicki said.

Notably, only one patient who was treated according to the EVADE protocol returned to the ED within 30 days, and that was a patient with issues related to alcohol abuse, she noted.

The findings suggest that mild DKA can be optimally managed in the setting of identification of the triggering factor, stabilization of glucose and electrolyte imbalances, patient education, and close follow-up, and that such management allows for more patients to be discharged from the ED, she said.

Ms. Chojnicki reported having no disclosures.

The EVADE protocol, step by step

The EVADE protocol for eligible patients begins with initiation of intravenous fluids but withholding insulin until initial labs are available. Once lab results confirm diabetic ketoacidosis, the staff initiates IV insulin.

A team including an attending endocrinologist, two nurse practitioners, and a certified diabetes educator are alerted when a patient is enrolled into the protocol.

Patients with all forms of DKA, including mild DKA without an anion gap, are managed on insulin drip with an endpoint goal of reaching a bicarbonate level of 21 mEq/L.

"The decision [to keep the patient in the ED for further observation and treatment or admit to the ICU] is based on the severity of the DKA and/or existing concurrent medical illness. If admitted to the ICU, the patient remains in the ICU arm of the DKA protocol, which involves frequent monitoring of glucose, electrolytes, venous blood gas, and urine output. Treatment is aimed at correcting the DKA and associated electrolyte disturbances," explained Maria Koen, a nurse practitioner and certified diabetes educator at Joslin Diabetes Center.

Regardless of whether the patient is admitted or remains in the ED, treatment involves the same IV insulin algorithm, which calls for no initial bolus; the starting rate is based on the initial finger stick, Ms. Koen noted.

Other features of the protocol include hourly finger sticks with adjustment of the dose with a goal of a target blood glucose of 100-180 mg/dL. Every 3 hours, someone on the team assesses venous blood gas and electrolytes.

IV fluid is run concurrently with IV insulin. Once the glucose drops to less than 250 mg/dL, fluid is changed to 5% dextrose in normal saline (D5NS). Once glucose increases again to 250 mg/dL, the protocol calls for discontinuation of D5NS with continuation of IV insulin infusion until the acidosis resolves.

If severe hypoglycemia occurs, D50 (50% dextrose) can be given as a bolus to reach the target of 100-180 mg/dL. The insulin drip is then resumed at 50% of the rate prior to the hypoglycemic event.

"Generally, we use normal saline or lactated Ringer’s as a first choice for IV fluid, at a rate of approximately 1 liter an hour for the first 4 hours, and this may be adjusted for patients who are at risk for volume overload, such as elders or patients with chronic kidney disease or congestive heart failure," she said.

After the first 4 hours, the IV solution may be changed to half of the normal saline, or half of the D5, if blood glucose drops below 250 mg/dL, at a rate of 125-250 cc per hour.

IV fluids may also be discontinued at this point if the patient is able to tolerate oral fluids.

The protocol also calls for electrolyte repletion as needed. Potassium may be added to each liter of IV fluid if the serum potassium reaches less than 5 mEq/L and the patient is voiding. The amount added is at the discretion of the attending physician, Ms. Koen said.

"Keep in mind that as the acidosis resolves, serum potassium will decrease. In such events, if severe hypokalemia occurs, it may be necessary to either decrease the insulin rate or temporarily hold the IV insulin drip," she said, noting that oral potassium and IV or oral phosphate can also be given once a patient can tolerate oral intake.

Insulin pumps should be removed to avoid overlap with the IV insulin, and the team should assess pump function and self-management.

Urine output and ability to tolerate oral intake should be assessed throughout the protocol, and patients should eat as soon as they are able to tolerate oral intake. The team should assess clinical status every 4 hours.

The patients’ care can move beyond the strictures of the protocol once they are either admitted to the ICU or stabilized in the ED. Those not admitted to the ICU can be discharged to home once their anion gap closes, their bicarbonate reaches more than 20 mEq/L, they can tolerate oral intake, and they successfully transition to a subcutaneous insulin regimen.

The transition to subcutaneous insulin requires that the basal dose be determined based on the patient’s home long-acting insulin dose or adjusted based on the nurse practitioner’s or doctor’s recommendations. Dosing for patients who are newly diagnosed or insulin naïve is calculated based on body weight in kilograms x 0.2.

When the patient is able to tolerate oral intake, prandial subcutaneous insulin based on the home prandial insulin dose should be initiated. Dosing in those who are insulin naïve should be based on body weight in kilograms x 0.2 and divided by 3 (but only with team recommendation).

"When transitioning from the IV insulin drip to subcutaneous insulin, if only basal insulin is given we recommend an overlap of the IV insulin drip for 2 hours. If both basal and prandial insulin are given at the same time, the recommendation is to overlap the insulin drip for at least 1 hour, and then the drip may be turned off," Ms. Koen said.

Insulin pumps may be restarted under the guidance of the certified diabetes educator. Electrolytes and glucose should be reassessed 2 hours after the insulin drip is stopped to ensure there is no return of the DKA.

Any patients with pH below 7.3, bicarbonate below 21 mEq/L, or an inability to tolerate oral intake will remain in the ED for continued observation and management. The patient is ready for discharge once pH is greater than 7.3, the anion gap closes, glucose reaches 250 mg/dL, and the patient can tolerate oral intake and has transitioned to subcutaneous insulin.

Following discharge, someone on the team should phone the patient, ideally within 24 hours, to ensure compliance with the postdischarge plan and schedule a follow-up clinic visit.

Ms. Koen reported having no disclosures.

ORLANDO – A new protocol for managing mild diabetic ketoacidosis in the emergency department led to a substantially improved discharge rate at a large teaching hospital.

Prior to development of the Emergency Valuable Approach and Diabetes Education (EVADE) protocol, almost all patients who presented with diabetic ketoacidosis (DKA) were admitted to the hospital, and most of those were admitted to the intensive care unit. However, in the most recent month for which outcomes data for the EVADE protocol are available, 24 of 106 patients (23%) managed according to the protocol were discharged from the ED and 82 were admitted, Marianne Chojnicki, a registered nurse and certified diabetes educator at the Joslin Diabetes Center, Boston, reported at the annual meeting of the American Association of Diabetes Educators.

The average length of stay in the ED for those who were discharged was 20 hours. The average length of stay in the hospital for 23 patients with a non-ICU admission was 136 hours, and the average length of stay in the ICU for 59 patients with an ICU admission was 33 hours, followed by 77 hours in the hospital after ICU discharge.

The findings have important implications for the care of patients presenting with DKA, which is documented in up to 9% of all hospital discharge summaries among patients with diabetes, and which is associated with mortality of up to 2%, Ms. Chojnicki noted.

"That’s a significant number of lives that are lost each year from a preventable event," she said.

In an effort to improve the discharge rate to at least 10%, Joslin Diabetes Center physicians, nurses, and diabetes educators worked together with Beth Israel Deaconess Medical Center in Boston to develop the EVADE protocol, which stemmed from a clinical approach used to manage DKA, and which is initiated in the ED based on clinical triggers.

They thought that a significant number of admissions were avoidable in a well-managed, coordinated system. The goal was to provide optimal cost-effective management for DKA, Ms. Chojnicki said.

From the outset, diabetes education was recognized as a key component of this protocol, she noted.

The education is individualized and covers multiple topics, such as identification of the circumstances leading up to DKA, a review of insulin action and technique of administration, and a review of ways to prevent DKA recurrence.

Evaluating the EVADE protocol

To evaluate the effectiveness of the protocol, a system was put in place to identify all patients who presented to the ED with blood glucose higher than 300 mg/dL and bicarbonate of 20 mEq/L or less. The patients were flagged for enrollment to be managed according to the EVADE protocol if their status was determined to be caused by DKA, and if they consented.

This process began in September 2013, and the first several months were spent refining management and defining quality indicators.

Month 8 results suggest that the protocol is effective for increasing discharge rates and reducing ICU admissions.

"Our initial goal was to discharge 10%, so we are above goal," Ms. Chojnicki said.

Overall, patients with mild to moderate DKA are going home from the ED, she said.

Typically, those with moderate DKA are admitted if they have a secondary diagnosis, and those patients are going to non-ICU beds.

"Only the sickest of the sick – basically those who are acidotic – are the patients going to the ICU," she said.

Preliminary data from an ongoing review of the results by a health economist show that despite the fact that the sickest patients are going to the ICU, the number of ICU days is decreasing in the wake of the EVADE protocol implementation.

This seems counterintuitive, but the latest data show that before EVADE, the average time spent in the ICU was 47.8 hours, and after EVADE the average time spent in the ICU was 31.6 hours.

"We shaved off 16.2 hours in one of the highest-cost areas of the hospital," Ms. Chojnicki said.

Notably, only one patient who was treated according to the EVADE protocol returned to the ED within 30 days, and that was a patient with issues related to alcohol abuse, she noted.

The findings suggest that mild DKA can be optimally managed in the setting of identification of the triggering factor, stabilization of glucose and electrolyte imbalances, patient education, and close follow-up, and that such management allows for more patients to be discharged from the ED, she said.

Ms. Chojnicki reported having no disclosures.

The EVADE protocol, step by step

The EVADE protocol for eligible patients begins with initiation of intravenous fluids but withholding insulin until initial labs are available. Once lab results confirm diabetic ketoacidosis, the staff initiates IV insulin.

A team including an attending endocrinologist, two nurse practitioners, and a certified diabetes educator are alerted when a patient is enrolled into the protocol.

Patients with all forms of DKA, including mild DKA without an anion gap, are managed on insulin drip with an endpoint goal of reaching a bicarbonate level of 21 mEq/L.

"The decision [to keep the patient in the ED for further observation and treatment or admit to the ICU] is based on the severity of the DKA and/or existing concurrent medical illness. If admitted to the ICU, the patient remains in the ICU arm of the DKA protocol, which involves frequent monitoring of glucose, electrolytes, venous blood gas, and urine output. Treatment is aimed at correcting the DKA and associated electrolyte disturbances," explained Maria Koen, a nurse practitioner and certified diabetes educator at Joslin Diabetes Center.

Regardless of whether the patient is admitted or remains in the ED, treatment involves the same IV insulin algorithm, which calls for no initial bolus; the starting rate is based on the initial finger stick, Ms. Koen noted.

Other features of the protocol include hourly finger sticks with adjustment of the dose with a goal of a target blood glucose of 100-180 mg/dL. Every 3 hours, someone on the team assesses venous blood gas and electrolytes.

IV fluid is run concurrently with IV insulin. Once the glucose drops to less than 250 mg/dL, fluid is changed to 5% dextrose in normal saline (D5NS). Once glucose increases again to 250 mg/dL, the protocol calls for discontinuation of D5NS with continuation of IV insulin infusion until the acidosis resolves.

If severe hypoglycemia occurs, D50 (50% dextrose) can be given as a bolus to reach the target of 100-180 mg/dL. The insulin drip is then resumed at 50% of the rate prior to the hypoglycemic event.

"Generally, we use normal saline or lactated Ringer’s as a first choice for IV fluid, at a rate of approximately 1 liter an hour for the first 4 hours, and this may be adjusted for patients who are at risk for volume overload, such as elders or patients with chronic kidney disease or congestive heart failure," she said.

After the first 4 hours, the IV solution may be changed to half of the normal saline, or half of the D5, if blood glucose drops below 250 mg/dL, at a rate of 125-250 cc per hour.

IV fluids may also be discontinued at this point if the patient is able to tolerate oral fluids.

The protocol also calls for electrolyte repletion as needed. Potassium may be added to each liter of IV fluid if the serum potassium reaches less than 5 mEq/L and the patient is voiding. The amount added is at the discretion of the attending physician, Ms. Koen said.

"Keep in mind that as the acidosis resolves, serum potassium will decrease. In such events, if severe hypokalemia occurs, it may be necessary to either decrease the insulin rate or temporarily hold the IV insulin drip," she said, noting that oral potassium and IV or oral phosphate can also be given once a patient can tolerate oral intake.

Insulin pumps should be removed to avoid overlap with the IV insulin, and the team should assess pump function and self-management.

Urine output and ability to tolerate oral intake should be assessed throughout the protocol, and patients should eat as soon as they are able to tolerate oral intake. The team should assess clinical status every 4 hours.

The patients’ care can move beyond the strictures of the protocol once they are either admitted to the ICU or stabilized in the ED. Those not admitted to the ICU can be discharged to home once their anion gap closes, their bicarbonate reaches more than 20 mEq/L, they can tolerate oral intake, and they successfully transition to a subcutaneous insulin regimen.

The transition to subcutaneous insulin requires that the basal dose be determined based on the patient’s home long-acting insulin dose or adjusted based on the nurse practitioner’s or doctor’s recommendations. Dosing for patients who are newly diagnosed or insulin naïve is calculated based on body weight in kilograms x 0.2.

When the patient is able to tolerate oral intake, prandial subcutaneous insulin based on the home prandial insulin dose should be initiated. Dosing in those who are insulin naïve should be based on body weight in kilograms x 0.2 and divided by 3 (but only with team recommendation).

"When transitioning from the IV insulin drip to subcutaneous insulin, if only basal insulin is given we recommend an overlap of the IV insulin drip for 2 hours. If both basal and prandial insulin are given at the same time, the recommendation is to overlap the insulin drip for at least 1 hour, and then the drip may be turned off," Ms. Koen said.

Insulin pumps may be restarted under the guidance of the certified diabetes educator. Electrolytes and glucose should be reassessed 2 hours after the insulin drip is stopped to ensure there is no return of the DKA.

Any patients with pH below 7.3, bicarbonate below 21 mEq/L, or an inability to tolerate oral intake will remain in the ED for continued observation and management. The patient is ready for discharge once pH is greater than 7.3, the anion gap closes, glucose reaches 250 mg/dL, and the patient can tolerate oral intake and has transitioned to subcutaneous insulin.

Following discharge, someone on the team should phone the patient, ideally within 24 hours, to ensure compliance with the postdischarge plan and schedule a follow-up clinic visit.

Ms. Koen reported having no disclosures.

ORLANDO – The field of diabetes education is evolving, especially as health reform is slowly changing the country’s health care landscape.

Deborah Greenwood, Ph.D., the 2014 president-elect for American Association of Diabetes Educators, talked with us during the AADE annual meeting about how the organization is assessing the changes and what it has planned.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – The field of diabetes education is evolving, especially as health reform is slowly changing the country’s health care landscape.

Deborah Greenwood, Ph.D., the 2014 president-elect for American Association of Diabetes Educators, talked with us during the AADE annual meeting about how the organization is assessing the changes and what it has planned.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – The field of diabetes education is evolving, especially as health reform is slowly changing the country’s health care landscape.

Deborah Greenwood, Ph.D., the 2014 president-elect for American Association of Diabetes Educators, talked with us during the AADE annual meeting about how the organization is assessing the changes and what it has planned.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Asking just a few questions about mental health from patients with type 2 diabetes helped identify underlying depression, and a consequent referral to a behavioral coach improved the patients’ mental health status and diabetes self-management skills, according to a pilot study in rural North Carolina.

The patients who had depression received three coaching sessions with a social worker over a 3- to 6-month period, and their hemoglobin A_1c dropped by 1%, while their depression scores were cut in half. "We also may have prevented 11 suicides," said Melissa Herman, who presented the poster at the American Academy of Diabetes Educators.

The findings could also mean that behavioral coaching may "improve diabetes self-management among those who do not present with depressive symptoms ... as an array of other tangible and intangible barriers may impede the patient’s ability to proper self-management," Ms. Herman and her colleagues wrote in their study.

The mental health aspect of diabetes care can go unnoticed and untreated if providers don’t open the conversation because of a lack of training, comfort, or resources. This could especially affect patients in rural areas where access to care is limited and many are uninsured and underinsured.

The FirstHealth Diabetes Self-Management Program began screening all patients for depression and anxiety in three rural counties in North Carolina where more than 60% of the population is below the poverty level, and the diabetes prevalence is 16%, compared with 9% statewide, Ms. Herman said. In addition, roughly 30% of patients with diabetes have depression.

"We realized that there really were no resources for patients who had underlying depression or other mental health issues," said Ms. Herman, a registered dietitian and certified diabetes educator who is the director of the diabetes program at FirstHealth of Carolinas.

"Folks were not asking or screening these individuals about depression, and we really felt like the depression interfered with their ability to take care of their diabetes, because the lack of jobs, lack of access to care, medication, and social issues trumped the diabetes care."

Five diabetes educators were trained to screen every patient for depression and anxiety with a Patient Health Questionnaire–2 tool or – PHQ-2. The tool was built into the electronic medical record.

Out of 2,233 patients screened from June 2011 to July 2013, a total of 222 were referred for behavioral health coaching with a social worker, and 181 kept their initial appointment. Those patients were further assessed with the PHQ-9, a more advanced questionnaire, and saw their coach an average of three times over a 3-month period.

Researchers found that in roughly 60% of the patients, the PHQ-9 scores improved by average of 50%, hinting at improvement in depressive symptoms.

Also, more than half of the patients had a 1% drop in the HbA_1c levels, from an average of 8.9% to an average of 7.8%.

The behavioral health coaches also negotiated 11 life contracts, which were used when there was a suspicion of self-harm. Those patients were also referred to psychiatric services.

Another important factor in success of the program was having a mental health coach who had a background in social work, health education, and diabetes knowledge. "This proved key to linking the behavior change to the influence of disease management," Ms. Herman and her colleagues wrote in their poster.

The team continues the program, even though the grant that initially funded the project has ended, "because it’s been phenomenal," said Ms. Herman. "It’s not time intensive, it’s just a matter of telling people that it’s okay to vent, and then give them some coping skills."

Ms. Herman had no disclosures.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Asking just a few questions about mental health from patients with type 2 diabetes helped identify underlying depression, and a consequent referral to a behavioral coach improved the patients’ mental health status and diabetes self-management skills, according to a pilot study in rural North Carolina.

The patients who had depression received three coaching sessions with a social worker over a 3- to 6-month period, and their hemoglobin A_1c dropped by 1%, while their depression scores were cut in half. "We also may have prevented 11 suicides," said Melissa Herman, who presented the poster at the American Academy of Diabetes Educators.

The findings could also mean that behavioral coaching may "improve diabetes self-management among those who do not present with depressive symptoms ... as an array of other tangible and intangible barriers may impede the patient’s ability to proper self-management," Ms. Herman and her colleagues wrote in their study.

The mental health aspect of diabetes care can go unnoticed and untreated if providers don’t open the conversation because of a lack of training, comfort, or resources. This could especially affect patients in rural areas where access to care is limited and many are uninsured and underinsured.

The FirstHealth Diabetes Self-Management Program began screening all patients for depression and anxiety in three rural counties in North Carolina where more than 60% of the population is below the poverty level, and the diabetes prevalence is 16%, compared with 9% statewide, Ms. Herman said. In addition, roughly 30% of patients with diabetes have depression.

"We realized that there really were no resources for patients who had underlying depression or other mental health issues," said Ms. Herman, a registered dietitian and certified diabetes educator who is the director of the diabetes program at FirstHealth of Carolinas.

"Folks were not asking or screening these individuals about depression, and we really felt like the depression interfered with their ability to take care of their diabetes, because the lack of jobs, lack of access to care, medication, and social issues trumped the diabetes care."

Five diabetes educators were trained to screen every patient for depression and anxiety with a Patient Health Questionnaire–2 tool or – PHQ-2. The tool was built into the electronic medical record.

Out of 2,233 patients screened from June 2011 to July 2013, a total of 222 were referred for behavioral health coaching with a social worker, and 181 kept their initial appointment. Those patients were further assessed with the PHQ-9, a more advanced questionnaire, and saw their coach an average of three times over a 3-month period.

Researchers found that in roughly 60% of the patients, the PHQ-9 scores improved by average of 50%, hinting at improvement in depressive symptoms.

Also, more than half of the patients had a 1% drop in the HbA_1c levels, from an average of 8.9% to an average of 7.8%.

The behavioral health coaches also negotiated 11 life contracts, which were used when there was a suspicion of self-harm. Those patients were also referred to psychiatric services.

Another important factor in success of the program was having a mental health coach who had a background in social work, health education, and diabetes knowledge. "This proved key to linking the behavior change to the influence of disease management," Ms. Herman and her colleagues wrote in their poster.

The team continues the program, even though the grant that initially funded the project has ended, "because it’s been phenomenal," said Ms. Herman. "It’s not time intensive, it’s just a matter of telling people that it’s okay to vent, and then give them some coping skills."

Ms. Herman had no disclosures.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Asking just a few questions about mental health from patients with type 2 diabetes helped identify underlying depression, and a consequent referral to a behavioral coach improved the patients’ mental health status and diabetes self-management skills, according to a pilot study in rural North Carolina.

The patients who had depression received three coaching sessions with a social worker over a 3- to 6-month period, and their hemoglobin A_1c dropped by 1%, while their depression scores were cut in half. "We also may have prevented 11 suicides," said Melissa Herman, who presented the poster at the American Academy of Diabetes Educators.

The findings could also mean that behavioral coaching may "improve diabetes self-management among those who do not present with depressive symptoms ... as an array of other tangible and intangible barriers may impede the patient’s ability to proper self-management," Ms. Herman and her colleagues wrote in their study.

The mental health aspect of diabetes care can go unnoticed and untreated if providers don’t open the conversation because of a lack of training, comfort, or resources. This could especially affect patients in rural areas where access to care is limited and many are uninsured and underinsured.

The FirstHealth Diabetes Self-Management Program began screening all patients for depression and anxiety in three rural counties in North Carolina where more than 60% of the population is below the poverty level, and the diabetes prevalence is 16%, compared with 9% statewide, Ms. Herman said. In addition, roughly 30% of patients with diabetes have depression.

"We realized that there really were no resources for patients who had underlying depression or other mental health issues," said Ms. Herman, a registered dietitian and certified diabetes educator who is the director of the diabetes program at FirstHealth of Carolinas.

"Folks were not asking or screening these individuals about depression, and we really felt like the depression interfered with their ability to take care of their diabetes, because the lack of jobs, lack of access to care, medication, and social issues trumped the diabetes care."

Five diabetes educators were trained to screen every patient for depression and anxiety with a Patient Health Questionnaire–2 tool or – PHQ-2. The tool was built into the electronic medical record.

Out of 2,233 patients screened from June 2011 to July 2013, a total of 222 were referred for behavioral health coaching with a social worker, and 181 kept their initial appointment. Those patients were further assessed with the PHQ-9, a more advanced questionnaire, and saw their coach an average of three times over a 3-month period.

Researchers found that in roughly 60% of the patients, the PHQ-9 scores improved by average of 50%, hinting at improvement in depressive symptoms.

Also, more than half of the patients had a 1% drop in the HbA_1c levels, from an average of 8.9% to an average of 7.8%.

The behavioral health coaches also negotiated 11 life contracts, which were used when there was a suspicion of self-harm. Those patients were also referred to psychiatric services.

Another important factor in success of the program was having a mental health coach who had a background in social work, health education, and diabetes knowledge. "This proved key to linking the behavior change to the influence of disease management," Ms. Herman and her colleagues wrote in their poster.

The team continues the program, even though the grant that initially funded the project has ended, "because it’s been phenomenal," said Ms. Herman. "It’s not time intensive, it’s just a matter of telling people that it’s okay to vent, and then give them some coping skills."

Ms. Herman had no disclosures.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Formal inpatient diabetes education can reduce hospital readmissions, a review of the literature suggested.

The education is most effective when it comes to helping patients understand discharge instructions and transition care, and when it involves an effort to improve health care literacy, Aiqun Liu, a registered nurse and certified diabetes educator at Barnes-Jewish Hospital at Washington University, St. Louis, reported at the annual meeting of the American Association of Diabetes Educators.

In 2008, about one in five hospitalizations was diabetes related, 20% of patients were readmitted within 30 days of discharge, and 26% were readmitted within 90 days, Ms. Liu found.

Most readmissions (87% in this review) are unplanned, and about 20% of the unplanned readmissions are potentially avoidable, she said.

Furthermore, these hospitalizations are a significant contributor to total health expenditures, accounting for nearly half of diabetes-related medical costs.

Health literacy is essential for successful self-care, but 15%-40% of patients with diabetes were found to have low health literacy, which is associated with less knowledge and skill with respect to self-management, more emergency department visits and hospital admissions, and poorer health outcomes, she said in an interview.

Based on 10 articles published between 2007 and 2013 that met prespecified search criteria, a number of educational strategies appear useful for improving health literacy and reducing readmissions, she said.

Focusing on discharge-related topics is particularly important. Such topics include blood glucose monitoring, medications, diet/nutrition, physical activity, warning signs that should prompt a call to the patient’s doctor, and lifestyle change related to illness.

Pharmacist-based interventions also were shown to be helpful and empowering. These included medication reconciliation, inpatient counseling, provision of simple adherence aids, and telephone follow-up after discharge, Ms. Liu noted.

Effective strategies for improving health literacy, self-care, and self-efficacy included pictograph-based discharge instructions, provision of health literacy– and numeracy-sensitive materials, clear communication between patients and providers, and use of the teach-back method to improve understanding and information retention.

The review also underscored the importance of transition care, providing patients with discharge instructions, appropriate prescriptions for diabetes medications and supplies, and making follow-up appointments proved most useful.

Individualized telephone follow-up after discharge is also important, Ms. Liu said.

In one study, formal inpatient diabetes education was associated with significantly reduced 30-day and 180-day readmission rates (P = .001 and .04, respectively).

The findings support the implementation of clinical protocols and interventions to support and improve health literacy; the use of literacy-sensitive materials and approaches to improve understanding of instructions and to enhance diabetes self-management; and training of health professionals regarding health literacy, numeracy, and clear communication techniques, she said, noting that additional research is needed to identify practical tools for improving health literacy in the inpatient setting.

Ms. Liu reported having no disclosures.

ORLANDO – Formal inpatient diabetes education can reduce hospital readmissions, a review of the literature suggested.

The education is most effective when it comes to helping patients understand discharge instructions and transition care, and when it involves an effort to improve health care literacy, Aiqun Liu, a registered nurse and certified diabetes educator at Barnes-Jewish Hospital at Washington University, St. Louis, reported at the annual meeting of the American Association of Diabetes Educators.

In 2008, about one in five hospitalizations was diabetes related, 20% of patients were readmitted within 30 days of discharge, and 26% were readmitted within 90 days, Ms. Liu found.

Most readmissions (87% in this review) are unplanned, and about 20% of the unplanned readmissions are potentially avoidable, she said.

Furthermore, these hospitalizations are a significant contributor to total health expenditures, accounting for nearly half of diabetes-related medical costs.

Health literacy is essential for successful self-care, but 15%-40% of patients with diabetes were found to have low health literacy, which is associated with less knowledge and skill with respect to self-management, more emergency department visits and hospital admissions, and poorer health outcomes, she said in an interview.

Based on 10 articles published between 2007 and 2013 that met prespecified search criteria, a number of educational strategies appear useful for improving health literacy and reducing readmissions, she said.

Focusing on discharge-related topics is particularly important. Such topics include blood glucose monitoring, medications, diet/nutrition, physical activity, warning signs that should prompt a call to the patient’s doctor, and lifestyle change related to illness.

Pharmacist-based interventions also were shown to be helpful and empowering. These included medication reconciliation, inpatient counseling, provision of simple adherence aids, and telephone follow-up after discharge, Ms. Liu noted.

Effective strategies for improving health literacy, self-care, and self-efficacy included pictograph-based discharge instructions, provision of health literacy– and numeracy-sensitive materials, clear communication between patients and providers, and use of the teach-back method to improve understanding and information retention.

The review also underscored the importance of transition care, providing patients with discharge instructions, appropriate prescriptions for diabetes medications and supplies, and making follow-up appointments proved most useful.

Individualized telephone follow-up after discharge is also important, Ms. Liu said.

In one study, formal inpatient diabetes education was associated with significantly reduced 30-day and 180-day readmission rates (P = .001 and .04, respectively).

The findings support the implementation of clinical protocols and interventions to support and improve health literacy; the use of literacy-sensitive materials and approaches to improve understanding of instructions and to enhance diabetes self-management; and training of health professionals regarding health literacy, numeracy, and clear communication techniques, she said, noting that additional research is needed to identify practical tools for improving health literacy in the inpatient setting.

Ms. Liu reported having no disclosures.

ORLANDO – Formal inpatient diabetes education can reduce hospital readmissions, a review of the literature suggested.

The education is most effective when it comes to helping patients understand discharge instructions and transition care, and when it involves an effort to improve health care literacy, Aiqun Liu, a registered nurse and certified diabetes educator at Barnes-Jewish Hospital at Washington University, St. Louis, reported at the annual meeting of the American Association of Diabetes Educators.

In 2008, about one in five hospitalizations was diabetes related, 20% of patients were readmitted within 30 days of discharge, and 26% were readmitted within 90 days, Ms. Liu found.

Most readmissions (87% in this review) are unplanned, and about 20% of the unplanned readmissions are potentially avoidable, she said.

Furthermore, these hospitalizations are a significant contributor to total health expenditures, accounting for nearly half of diabetes-related medical costs.

Health literacy is essential for successful self-care, but 15%-40% of patients with diabetes were found to have low health literacy, which is associated with less knowledge and skill with respect to self-management, more emergency department visits and hospital admissions, and poorer health outcomes, she said in an interview.

Based on 10 articles published between 2007 and 2013 that met prespecified search criteria, a number of educational strategies appear useful for improving health literacy and reducing readmissions, she said.

Focusing on discharge-related topics is particularly important. Such topics include blood glucose monitoring, medications, diet/nutrition, physical activity, warning signs that should prompt a call to the patient’s doctor, and lifestyle change related to illness.

Pharmacist-based interventions also were shown to be helpful and empowering. These included medication reconciliation, inpatient counseling, provision of simple adherence aids, and telephone follow-up after discharge, Ms. Liu noted.

Effective strategies for improving health literacy, self-care, and self-efficacy included pictograph-based discharge instructions, provision of health literacy– and numeracy-sensitive materials, clear communication between patients and providers, and use of the teach-back method to improve understanding and information retention.

The review also underscored the importance of transition care, providing patients with discharge instructions, appropriate prescriptions for diabetes medications and supplies, and making follow-up appointments proved most useful.

Individualized telephone follow-up after discharge is also important, Ms. Liu said.

In one study, formal inpatient diabetes education was associated with significantly reduced 30-day and 180-day readmission rates (P = .001 and .04, respectively).

The findings support the implementation of clinical protocols and interventions to support and improve health literacy; the use of literacy-sensitive materials and approaches to improve understanding of instructions and to enhance diabetes self-management; and training of health professionals regarding health literacy, numeracy, and clear communication techniques, she said, noting that additional research is needed to identify practical tools for improving health literacy in the inpatient setting.

Ms. Liu reported having no disclosures.

ORLANDO – Nearly a decade after the results of the Diabetes Attitudes Wishes and Needs (DAWN) trial showed that the emotional health of patients with diabetes was not being adequately addressed, findings from the DAWN2 trial show that not much has changed in that regard.

Almost half of the more than 8,500 patients with diabetes who participated in the multinational DAWN2 trial reported experiencing emotional distress as a result of their diabetes, and 14% had likely clinical depression. The results also show that most patients with diabetes want to improve self-management, and that having a large social support network is associated with better psychosocial outcomes.

At the annual meeting of the American Association of Diabetes Educators, Martha Funnell, a certified diabetes educator, associate research scientist at the University of Michigan, Ann Arbor, and a member of the advisory committee for the Novo Nordisk–sponsored DAWN trials, discussed the findings and their clinical implications.

ORLANDO – Nearly a decade after the results of the Diabetes Attitudes Wishes and Needs (DAWN) trial showed that the emotional health of patients with diabetes was not being adequately addressed, findings from the DAWN2 trial show that not much has changed in that regard.

Almost half of the more than 8,500 patients with diabetes who participated in the multinational DAWN2 trial reported experiencing emotional distress as a result of their diabetes, and 14% had likely clinical depression. The results also show that most patients with diabetes want to improve self-management, and that having a large social support network is associated with better psychosocial outcomes.

At the annual meeting of the American Association of Diabetes Educators, Martha Funnell, a certified diabetes educator, associate research scientist at the University of Michigan, Ann Arbor, and a member of the advisory committee for the Novo Nordisk–sponsored DAWN trials, discussed the findings and their clinical implications.

ORLANDO – Nearly a decade after the results of the Diabetes Attitudes Wishes and Needs (DAWN) trial showed that the emotional health of patients with diabetes was not being adequately addressed, findings from the DAWN2 trial show that not much has changed in that regard.

Almost half of the more than 8,500 patients with diabetes who participated in the multinational DAWN2 trial reported experiencing emotional distress as a result of their diabetes, and 14% had likely clinical depression. The results also show that most patients with diabetes want to improve self-management, and that having a large social support network is associated with better psychosocial outcomes.

At the annual meeting of the American Association of Diabetes Educators, Martha Funnell, a certified diabetes educator, associate research scientist at the University of Michigan, Ann Arbor, and a member of the advisory committee for the Novo Nordisk–sponsored DAWN trials, discussed the findings and their clinical implications.

ORLANDO – Emotional distress associated with a diabetes diagnosis explains many patients’ difficulties with self-management, based on results from the DAWN2 study presented at the annual meeting of the American Association of Diabetes Educators.

The Novo Nordisk–sponsored DAWN2 (Diabetes Attitudes Wishes and Needs 2) study included 15,438 adults from 17 countries: 8,596 were people with diabetes (1,368 with type 1 and 7,228 with type 2), 2,057 were family members of people with diabetes, and 4,785 were health care providers. The researchers set out primarily to determine the factors that prevent and facilitate active and successful diabetes management.

"The ultimate goal for all of us and for this study is to enable all people with diabetes to live full, healthy, and productive lives, and to be engaged in their own care, preserving their health, and improving their quality of life," said Martha Funnell, a certified diabetes educator, associate research scientist at the University of Michigan, Ann Arbor, and a member of an advisory panel for the DAWN studies.

The first results from DAWN, published in 2005 and 2006, indicated that the psychosocial needs of patients with diabetes were not being met. The findings were based on the results of a survey that covered a broad range of topics, such as health and quality of life, attitudes and beliefs about diabetes, diabetes training, care and support, active self-management, and diabetes education and information. The first global benchmarking results were published in three articles in Diabetic Medicine (Diabet. Med. 2013;30:767-98).

Although a number of themes emerged from the DAWN findings, those with respect to emotional health stand out. In response to those results, emotional well-being has been incorporated into standards of care, Ms. Funnell said. In DAWN2, slightly more patients reported experiencing ongoing emotional distress as a result of diabetes (45% vs. 43%); 14% likely had clinical depression as a result of their diagnosis.

The findings are concerning as emotional distress – feelings of anger, fear, frustration, sadness, and guilt – are among the biggest influencers of self-management. Further, diabetes-related distress has an adverse impact on outcomes, including hemoglobin A_1c levels, dietary and exercise behaviors, quality of life, and depression, Ms. Funnell said.

Diabetes also affects other aspects of life: 44% of people with diabetes in DAWN2 said their finances were affected, 38% said leisure activities were affected, 35% said that work and studies were affected, and 21% reported problems with family and peer relationships.

"We have to address diabetes-related distress if we want our patients to make changes and improve their outcomes," she said.

Notably, 52% of health care providers in DAWN2 reported asking patients how their life was affected by diabetes, yet only 24% of patients said their health care provider asked them that question.

"If I was going to do a one-question educational assessment, that would be the question [I would ask] because that tells pretty much all I need to know to work with that person," Ms. Funnell said.

Other findings from DAWN2 included the following:

• Family members of diabetes patients are burdened by the disease as well; 39% said they wanted to be more involved and 37% said they didn’t know how to be more involved.

• Most people with diabetes said that they want to be actively engaged and to participate in their care, but most aren’t.

• Half of the respondents with diabetes had never participated in a diabetes education program.

• Health care providers report a desire for more training in many aspects of diabetes care.

• Discrimination because of diabetes was reported by 19% of patients, implying a lack of awareness about diabetes.

An analysis of U.S.-only data from DAWN2 also shed light on important issues related to diabetes care and self-management.

The more than 500 U.S. respondents with diabetes in the DAWN2 study reported following a healthy eating plan for a mean of 4.7 days per week. They participated in at least 30 minutes of physical activity on a mean of 2.7 days per week and 65% expressed a desire to improve on this measure. Patients tested their blood sugar levels as recommended by their health care provider a mean of 4.5 days per week and took all medication as prescribed on a mean of 6.4 days per week. They checked their feet on a mean of 4.7 days per week (Curr. Med. Res. Opin. 2014 July 31:1-39).

Adherence varied considerably by ethnic group. For example, non-Hispanic white patients had the lowest scores for physical activity, Chinese Americans had the lowest scores for testing their blood sugar as recommended, and African Americans and Hispanics had the best scores for checking their feet.

Psychological outcomes also differed by ethnicity. African Americans had the best scores and non-Hispanic whites had the worst scores for well-being, quality of life, diabetes empowerment, and diabetes impact. Hispanics had the worst scores for quality of life and diabetes distress.

The DAWN2 data for U.S. survey respondents also indicated a substantial level of distress among people with diabetes and their family members. Having a large social support network for diabetes was related to better psychosocial outcomes, but few people with diabetes let others know how they can best provide support.

Also, U.S. respondents were pleased with the level of involvement of their family in diabetes care, and they feel that family members help a great deal by listening to them when they talk about difficulties associated with living with diabetes.

Diabetes is a burden from a management and psychological perspective. Patients need to be encouraged to ask for support when it is needed, and clinicians need to recognize that family members are untapped resources for patient support as well as a group in need of support as they deal with the burdens of caring for a family member with diabetes, Ms. Funnell added.

"Finally, we absolutely have to involve the person with diabetes and their family members as equal partners when developing care solutions," she said. Family members need to be taught how to help, and patients need to be asked how diabetes is affecting their life to identify problems and set appropriate goals for solving them.

"We need to truly focus on patient-centered care. ... We really need to surround the patient with their family and their friends, their health care, their communities, their workplaces, and the larger society if they are going to be successful in their self-management. It takes a village to manage diabetes, and every one of us has a role to play to make person-centered diabetes care and patient-centered diabetes education and ongoing support the reality that it needs to be," she said.

Ms. Funnell reported serving as a board or advisory panel member for Novo Nordisk, the sponsor of DAWN2, as well as several other drug companies involved in diabetes care, and receiving grant funding from BMS Foundation.

ORLANDO – Emotional distress associated with a diabetes diagnosis explains many patients’ difficulties with self-management, based on results from the DAWN2 study presented at the annual meeting of the American Association of Diabetes Educators.

The Novo Nordisk–sponsored DAWN2 (Diabetes Attitudes Wishes and Needs 2) study included 15,438 adults from 17 countries: 8,596 were people with diabetes (1,368 with type 1 and 7,228 with type 2), 2,057 were family members of people with diabetes, and 4,785 were health care providers. The researchers set out primarily to determine the factors that prevent and facilitate active and successful diabetes management.

"The ultimate goal for all of us and for this study is to enable all people with diabetes to live full, healthy, and productive lives, and to be engaged in their own care, preserving their health, and improving their quality of life," said Martha Funnell, a certified diabetes educator, associate research scientist at the University of Michigan, Ann Arbor, and a member of an advisory panel for the DAWN studies.

The first results from DAWN, published in 2005 and 2006, indicated that the psychosocial needs of patients with diabetes were not being met. The findings were based on the results of a survey that covered a broad range of topics, such as health and quality of life, attitudes and beliefs about diabetes, diabetes training, care and support, active self-management, and diabetes education and information. The first global benchmarking results were published in three articles in Diabetic Medicine (Diabet. Med. 2013;30:767-98).

Although a number of themes emerged from the DAWN findings, those with respect to emotional health stand out. In response to those results, emotional well-being has been incorporated into standards of care, Ms. Funnell said. In DAWN2, slightly more patients reported experiencing ongoing emotional distress as a result of diabetes (45% vs. 43%); 14% likely had clinical depression as a result of their diagnosis.

The findings are concerning as emotional distress – feelings of anger, fear, frustration, sadness, and guilt – are among the biggest influencers of self-management. Further, diabetes-related distress has an adverse impact on outcomes, including hemoglobin A_1c levels, dietary and exercise behaviors, quality of life, and depression, Ms. Funnell said.

Diabetes also affects other aspects of life: 44% of people with diabetes in DAWN2 said their finances were affected, 38% said leisure activities were affected, 35% said that work and studies were affected, and 21% reported problems with family and peer relationships.

"We have to address diabetes-related distress if we want our patients to make changes and improve their outcomes," she said.

Notably, 52% of health care providers in DAWN2 reported asking patients how their life was affected by diabetes, yet only 24% of patients said their health care provider asked them that question.

"If I was going to do a one-question educational assessment, that would be the question [I would ask] because that tells pretty much all I need to know to work with that person," Ms. Funnell said.

Other findings from DAWN2 included the following:

• Family members of diabetes patients are burdened by the disease as well; 39% said they wanted to be more involved and 37% said they didn’t know how to be more involved.

• Most people with diabetes said that they want to be actively engaged and to participate in their care, but most aren’t.

• Half of the respondents with diabetes had never participated in a diabetes education program.

• Health care providers report a desire for more training in many aspects of diabetes care.

• Discrimination because of diabetes was reported by 19% of patients, implying a lack of awareness about diabetes.

An analysis of U.S.-only data from DAWN2 also shed light on important issues related to diabetes care and self-management.

The more than 500 U.S. respondents with diabetes in the DAWN2 study reported following a healthy eating plan for a mean of 4.7 days per week. They participated in at least 30 minutes of physical activity on a mean of 2.7 days per week and 65% expressed a desire to improve on this measure. Patients tested their blood sugar levels as recommended by their health care provider a mean of 4.5 days per week and took all medication as prescribed on a mean of 6.4 days per week. They checked their feet on a mean of 4.7 days per week (Curr. Med. Res. Opin. 2014 July 31:1-39).

Adherence varied considerably by ethnic group. For example, non-Hispanic white patients had the lowest scores for physical activity, Chinese Americans had the lowest scores for testing their blood sugar as recommended, and African Americans and Hispanics had the best scores for checking their feet.

Psychological outcomes also differed by ethnicity. African Americans had the best scores and non-Hispanic whites had the worst scores for well-being, quality of life, diabetes empowerment, and diabetes impact. Hispanics had the worst scores for quality of life and diabetes distress.

The DAWN2 data for U.S. survey respondents also indicated a substantial level of distress among people with diabetes and their family members. Having a large social support network for diabetes was related to better psychosocial outcomes, but few people with diabetes let others know how they can best provide support.

Also, U.S. respondents were pleased with the level of involvement of their family in diabetes care, and they feel that family members help a great deal by listening to them when they talk about difficulties associated with living with diabetes.

Diabetes is a burden from a management and psychological perspective. Patients need to be encouraged to ask for support when it is needed, and clinicians need to recognize that family members are untapped resources for patient support as well as a group in need of support as they deal with the burdens of caring for a family member with diabetes, Ms. Funnell added.

"Finally, we absolutely have to involve the person with diabetes and their family members as equal partners when developing care solutions," she said. Family members need to be taught how to help, and patients need to be asked how diabetes is affecting their life to identify problems and set appropriate goals for solving them.

"We need to truly focus on patient-centered care. ... We really need to surround the patient with their family and their friends, their health care, their communities, their workplaces, and the larger society if they are going to be successful in their self-management. It takes a village to manage diabetes, and every one of us has a role to play to make person-centered diabetes care and patient-centered diabetes education and ongoing support the reality that it needs to be," she said.

Ms. Funnell reported serving as a board or advisory panel member for Novo Nordisk, the sponsor of DAWN2, as well as several other drug companies involved in diabetes care, and receiving grant funding from BMS Foundation.

ORLANDO – Emotional distress associated with a diabetes diagnosis explains many patients’ difficulties with self-management, based on results from the DAWN2 study presented at the annual meeting of the American Association of Diabetes Educators.

The Novo Nordisk–sponsored DAWN2 (Diabetes Attitudes Wishes and Needs 2) study included 15,438 adults from 17 countries: 8,596 were people with diabetes (1,368 with type 1 and 7,228 with type 2), 2,057 were family members of people with diabetes, and 4,785 were health care providers. The researchers set out primarily to determine the factors that prevent and facilitate active and successful diabetes management.

"The ultimate goal for all of us and for this study is to enable all people with diabetes to live full, healthy, and productive lives, and to be engaged in their own care, preserving their health, and improving their quality of life," said Martha Funnell, a certified diabetes educator, associate research scientist at the University of Michigan, Ann Arbor, and a member of an advisory panel for the DAWN studies.

The first results from DAWN, published in 2005 and 2006, indicated that the psychosocial needs of patients with diabetes were not being met. The findings were based on the results of a survey that covered a broad range of topics, such as health and quality of life, attitudes and beliefs about diabetes, diabetes training, care and support, active self-management, and diabetes education and information. The first global benchmarking results were published in three articles in Diabetic Medicine (Diabet. Med. 2013;30:767-98).

Although a number of themes emerged from the DAWN findings, those with respect to emotional health stand out. In response to those results, emotional well-being has been incorporated into standards of care, Ms. Funnell said. In DAWN2, slightly more patients reported experiencing ongoing emotional distress as a result of diabetes (45% vs. 43%); 14% likely had clinical depression as a result of their diagnosis.

The findings are concerning as emotional distress – feelings of anger, fear, frustration, sadness, and guilt – are among the biggest influencers of self-management. Further, diabetes-related distress has an adverse impact on outcomes, including hemoglobin A_1c levels, dietary and exercise behaviors, quality of life, and depression, Ms. Funnell said.

Diabetes also affects other aspects of life: 44% of people with diabetes in DAWN2 said their finances were affected, 38% said leisure activities were affected, 35% said that work and studies were affected, and 21% reported problems with family and peer relationships.

"We have to address diabetes-related distress if we want our patients to make changes and improve their outcomes," she said.

Notably, 52% of health care providers in DAWN2 reported asking patients how their life was affected by diabetes, yet only 24% of patients said their health care provider asked them that question.

"If I was going to do a one-question educational assessment, that would be the question [I would ask] because that tells pretty much all I need to know to work with that person," Ms. Funnell said.

Other findings from DAWN2 included the following:

• Family members of diabetes patients are burdened by the disease as well; 39% said they wanted to be more involved and 37% said they didn’t know how to be more involved.

• Most people with diabetes said that they want to be actively engaged and to participate in their care, but most aren’t.

• Half of the respondents with diabetes had never participated in a diabetes education program.

• Health care providers report a desire for more training in many aspects of diabetes care.

• Discrimination because of diabetes was reported by 19% of patients, implying a lack of awareness about diabetes.

An analysis of U.S.-only data from DAWN2 also shed light on important issues related to diabetes care and self-management.

The more than 500 U.S. respondents with diabetes in the DAWN2 study reported following a healthy eating plan for a mean of 4.7 days per week. They participated in at least 30 minutes of physical activity on a mean of 2.7 days per week and 65% expressed a desire to improve on this measure. Patients tested their blood sugar levels as recommended by their health care provider a mean of 4.5 days per week and took all medication as prescribed on a mean of 6.4 days per week. They checked their feet on a mean of 4.7 days per week (Curr. Med. Res. Opin. 2014 July 31:1-39).

Adherence varied considerably by ethnic group. For example, non-Hispanic white patients had the lowest scores for physical activity, Chinese Americans had the lowest scores for testing their blood sugar as recommended, and African Americans and Hispanics had the best scores for checking their feet.

Psychological outcomes also differed by ethnicity. African Americans had the best scores and non-Hispanic whites had the worst scores for well-being, quality of life, diabetes empowerment, and diabetes impact. Hispanics had the worst scores for quality of life and diabetes distress.

The DAWN2 data for U.S. survey respondents also indicated a substantial level of distress among people with diabetes and their family members. Having a large social support network for diabetes was related to better psychosocial outcomes, but few people with diabetes let others know how they can best provide support.

Also, U.S. respondents were pleased with the level of involvement of their family in diabetes care, and they feel that family members help a great deal by listening to them when they talk about difficulties associated with living with diabetes.

Diabetes is a burden from a management and psychological perspective. Patients need to be encouraged to ask for support when it is needed, and clinicians need to recognize that family members are untapped resources for patient support as well as a group in need of support as they deal with the burdens of caring for a family member with diabetes, Ms. Funnell added.

"Finally, we absolutely have to involve the person with diabetes and their family members as equal partners when developing care solutions," she said. Family members need to be taught how to help, and patients need to be asked how diabetes is affecting their life to identify problems and set appropriate goals for solving them.

"We need to truly focus on patient-centered care. ... We really need to surround the patient with their family and their friends, their health care, their communities, their workplaces, and the larger society if they are going to be successful in their self-management. It takes a village to manage diabetes, and every one of us has a role to play to make person-centered diabetes care and patient-centered diabetes education and ongoing support the reality that it needs to be," she said.

Ms. Funnell reported serving as a board or advisory panel member for Novo Nordisk, the sponsor of DAWN2, as well as several other drug companies involved in diabetes care, and receiving grant funding from BMS Foundation.

ORLANDO – Susan Weiner has been on the diabetes education front line for nearly 25 years, and she was just elected as Educator of the Year for her "special contributions to the field through dedication, innovation, and sensitivity in patient care" at the annual meeting of the American Association of Diabetes Educators.

Ms. Weiner, who is in private practice in Long Island, New York, also recently wrote a book, "The Complete Diabetes Organizer," to help patients organize various aspects of their lives so that they can successfully manage their diabetes.

In a video interview, Ms. Weiner shares some of her advice with physicians.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Susan Weiner has been on the diabetes education front line for nearly 25 years, and she was just elected as Educator of the Year for her "special contributions to the field through dedication, innovation, and sensitivity in patient care" at the annual meeting of the American Association of Diabetes Educators.

Ms. Weiner, who is in private practice in Long Island, New York, also recently wrote a book, "The Complete Diabetes Organizer," to help patients organize various aspects of their lives so that they can successfully manage their diabetes.

In a video interview, Ms. Weiner shares some of her advice with physicians.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – Susan Weiner has been on the diabetes education front line for nearly 25 years, and she was just elected as Educator of the Year for her "special contributions to the field through dedication, innovation, and sensitivity in patient care" at the annual meeting of the American Association of Diabetes Educators.

Ms. Weiner, who is in private practice in Long Island, New York, also recently wrote a book, "The Complete Diabetes Organizer," to help patients organize various aspects of their lives so that they can successfully manage their diabetes.

In a video interview, Ms. Weiner shares some of her advice with physicians.

nmiller@frontlinemedcom.com

On Twitter @naseemmiller

ORLANDO – A low-fat vegan diet reduced symptoms of peripheral neuropathy among patients with type 2 diabetes in the randomized, controlled Dietary Intervention for Chronic Diabetic Neuropathy Pain (DINE) study.

After 20 weeks, 17 patients who were assigned to the vegan diet group were more likely than were 18 control patients to have lost weight, to have reductions in pain scores, and to have neurologic improvements in their foot neuropathy.

©KaterynaSednieva/Thinkstock

The findings demonstrate "the potential of a low-fat vegan diet as a treatment for diabetic neuropathy pain," Anne E. Bunner, Ph.D., reported at the annual meeting of the American Association of Diabetes Educators. Other treatment options for diabetic neuropathy offer pain relief, but do not address the underlying nerve damage.

Support measures are needed to ensure the success of major dietary changes, said Dr. Bunner, associate director for clinical research at the Physicians Committee for Responsible Medicine, Washington, D.C.

The findings confirm those of a prior uncontrolled study (J. Nutr. Med. 1994;4:431-9) in which 81% of patients had pain relief with a low-fat, high-fiber vegan diet, Dr. Bunner said. A review of five studies involving more than 16,000 patients with type 2 diabetes showed that tight blood glucose control reduces the severity of diabetic neuropathy but does not eliminate the associated pain.

Dr. Bunner reported that the mean change scores in the diet group vs. the control group were –7.0 vs. –0.7 for body weight, –2.4 vs. –0.2 for body mass index, –9.1 vs. –0.9 for McGill Pain Questionnaire results, and 0.7 vs. –11.7 for foot conductance.

The diet group also experienced improvements in mean change scores for hemoglobin A_1c (–0.8), Quality of Life score (–8.4), and Neuropathy Total Symptoms Score (–3.9), but the changes in these scores were not significantly better than those of the control group (–0.1, –4.7, –2.7, respectively).

The control group experienced greater improvements in pain as measured by a visual analogue scale (mean change scores of –1.2 and –2.1* for the diet and control groups, respectively). The change in the diet group was not statistically significant.

Patients in both groups used vitamin B₁₂ supplements during the course of the study, which could explain the improvements in the control group, Dr. Bunner said. B₁₂ deficiency is associated with diabetic neuropathy, but none of the patients had a B₁₂ deficiency at baseline. It is possible that B₁₂ may have been an active treatment or that the motivation associated with being a study participant was associated with the improvements.

Of note, 4 of 17 patients in the diet group were able to reduce the dosages of lipid-lowering medications; 1 increased the dosage. No one in the control group was able to reduce the dosages of lipid-lowering medications; 3 of 18 increased dosages. Ten of 17 diet group patients reduced the dosages of diabetes medications, and 2 of 18 controls reduced the dosages of diabetes medications.

Mean age of the study subjects was 57 years. Those assigned to the diet group were instructed to consume only plant foods, and to limit intake of oils, nuts, and fatty foods. Fat was limited to 3 g per serving or 20-30 g per day. Patients in the diet group also were advised to include 40 g/day of high-fiber foods, and to consume low–glycemic index foods. No limit was placed on portions.

The diet group participated in weekly classes involving nutrition education, social support, cooking demonstrations, and food product sampling.

Both groups used B₁₂ supplements, and the control group was instructed to make no major dietary changes during the 20-week study.

Thirteen of 17 diet group patients were fully compliant with the vegan diet; 8 of the 13 were compliant with the low-fat instructions at both the 10- and 20-week assessment, and 3 of the 13 were compliant with the low-fat instructions at one of the two assessments. Two were fully compliant with the low-fat guidelines, but not the vegan guidelines, and two were noncompliant with both. One patient did not complete the study.

Dr. Bunner reported having no disclosures.

CORRECTED Aug 8: Improvement in pain in the control group, as measured by a visual analogue scale, was misstated in the original story. That value was –2.1.

ORLANDO – A low-fat vegan diet reduced symptoms of peripheral neuropathy among patients with type 2 diabetes in the randomized, controlled Dietary Intervention for Chronic Diabetic Neuropathy Pain (DINE) study.

After 20 weeks, 17 patients who were assigned to the vegan diet group were more likely than were 18 control patients to have lost weight, to have reductions in pain scores, and to have neurologic improvements in their foot neuropathy.

©KaterynaSednieva/Thinkstock

The findings demonstrate "the potential of a low-fat vegan diet as a treatment for diabetic neuropathy pain," Anne E. Bunner, Ph.D., reported at the annual meeting of the American Association of Diabetes Educators. Other treatment options for diabetic neuropathy offer pain relief, but do not address the underlying nerve damage.

Support measures are needed to ensure the success of major dietary changes, said Dr. Bunner, associate director for clinical research at the Physicians Committee for Responsible Medicine, Washington, D.C.

The findings confirm those of a prior uncontrolled study (J. Nutr. Med. 1994;4:431-9) in which 81% of patients had pain relief with a low-fat, high-fiber vegan diet, Dr. Bunner said. A review of five studies involving more than 16,000 patients with type 2 diabetes showed that tight blood glucose control reduces the severity of diabetic neuropathy but does not eliminate the associated pain.

Dr. Bunner reported that the mean change scores in the diet group vs. the control group were –7.0 vs. –0.7 for body weight, –2.4 vs. –0.2 for body mass index, –9.1 vs. –0.9 for McGill Pain Questionnaire results, and 0.7 vs. –11.7 for foot conductance.

The diet group also experienced improvements in mean change scores for hemoglobin A_1c (–0.8), Quality of Life score (–8.4), and Neuropathy Total Symptoms Score (–3.9), but the changes in these scores were not significantly better than those of the control group (–0.1, –4.7, –2.7, respectively).

The control group experienced greater improvements in pain as measured by a visual analogue scale (mean change scores of –1.2 and –2.1* for the diet and control groups, respectively). The change in the diet group was not statistically significant.

Patients in both groups used vitamin B₁₂ supplements during the course of the study, which could explain the improvements in the control group, Dr. Bunner said. B₁₂ deficiency is associated with diabetic neuropathy, but none of the patients had a B₁₂ deficiency at baseline. It is possible that B₁₂ may have been an active treatment or that the motivation associated with being a study participant was associated with the improvements.

Of note, 4 of 17 patients in the diet group were able to reduce the dosages of lipid-lowering medications; 1 increased the dosage. No one in the control group was able to reduce the dosages of lipid-lowering medications; 3 of 18 increased dosages. Ten of 17 diet group patients reduced the dosages of diabetes medications, and 2 of 18 controls reduced the dosages of diabetes medications.

Mean age of the study subjects was 57 years. Those assigned to the diet group were instructed to consume only plant foods, and to limit intake of oils, nuts, and fatty foods. Fat was limited to 3 g per serving or 20-30 g per day. Patients in the diet group also were advised to include 40 g/day of high-fiber foods, and to consume low–glycemic index foods. No limit was placed on portions.

The diet group participated in weekly classes involving nutrition education, social support, cooking demonstrations, and food product sampling.

Both groups used B₁₂ supplements, and the control group was instructed to make no major dietary changes during the 20-week study.

Thirteen of 17 diet group patients were fully compliant with the vegan diet; 8 of the 13 were compliant with the low-fat instructions at both the 10- and 20-week assessment, and 3 of the 13 were compliant with the low-fat instructions at one of the two assessments. Two were fully compliant with the low-fat guidelines, but not the vegan guidelines, and two were noncompliant with both. One patient did not complete the study.

Dr. Bunner reported having no disclosures.

CORRECTED Aug 8: Improvement in pain in the control group, as measured by a visual analogue scale, was misstated in the original story. That value was –2.1.

ORLANDO – A low-fat vegan diet reduced symptoms of peripheral neuropathy among patients with type 2 diabetes in the randomized, controlled Dietary Intervention for Chronic Diabetic Neuropathy Pain (DINE) study.

After 20 weeks, 17 patients who were assigned to the vegan diet group were more likely than were 18 control patients to have lost weight, to have reductions in pain scores, and to have neurologic improvements in their foot neuropathy.

©KaterynaSednieva/Thinkstock

The findings demonstrate "the potential of a low-fat vegan diet as a treatment for diabetic neuropathy pain," Anne E. Bunner, Ph.D., reported at the annual meeting of the American Association of Diabetes Educators. Other treatment options for diabetic neuropathy offer pain relief, but do not address the underlying nerve damage.

Support measures are needed to ensure the success of major dietary changes, said Dr. Bunner, associate director for clinical research at the Physicians Committee for Responsible Medicine, Washington, D.C.

The findings confirm those of a prior uncontrolled study (J. Nutr. Med. 1994;4:431-9) in which 81% of patients had pain relief with a low-fat, high-fiber vegan diet, Dr. Bunner said. A review of five studies involving more than 16,000 patients with type 2 diabetes showed that tight blood glucose control reduces the severity of diabetic neuropathy but does not eliminate the associated pain.

Dr. Bunner reported that the mean change scores in the diet group vs. the control group were –7.0 vs. –0.7 for body weight, –2.4 vs. –0.2 for body mass index, –9.1 vs. –0.9 for McGill Pain Questionnaire results, and 0.7 vs. –11.7 for foot conductance.

The diet group also experienced improvements in mean change scores for hemoglobin A_1c (–0.8), Quality of Life score (–8.4), and Neuropathy Total Symptoms Score (–3.9), but the changes in these scores were not significantly better than those of the control group (–0.1, –4.7, –2.7, respectively).

The control group experienced greater improvements in pain as measured by a visual analogue scale (mean change scores of –1.2 and –2.1* for the diet and control groups, respectively). The change in the diet group was not statistically significant.

Patients in both groups used vitamin B₁₂ supplements during the course of the study, which could explain the improvements in the control group, Dr. Bunner said. B₁₂ deficiency is associated with diabetic neuropathy, but none of the patients had a B₁₂ deficiency at baseline. It is possible that B₁₂ may have been an active treatment or that the motivation associated with being a study participant was associated with the improvements.

Of note, 4 of 17 patients in the diet group were able to reduce the dosages of lipid-lowering medications; 1 increased the dosage. No one in the control group was able to reduce the dosages of lipid-lowering medications; 3 of 18 increased dosages. Ten of 17 diet group patients reduced the dosages of diabetes medications, and 2 of 18 controls reduced the dosages of diabetes medications.

Mean age of the study subjects was 57 years. Those assigned to the diet group were instructed to consume only plant foods, and to limit intake of oils, nuts, and fatty foods. Fat was limited to 3 g per serving or 20-30 g per day. Patients in the diet group also were advised to include 40 g/day of high-fiber foods, and to consume low–glycemic index foods. No limit was placed on portions.

The diet group participated in weekly classes involving nutrition education, social support, cooking demonstrations, and food product sampling.

Both groups used B₁₂ supplements, and the control group was instructed to make no major dietary changes during the 20-week study.

Thirteen of 17 diet group patients were fully compliant with the vegan diet; 8 of the 13 were compliant with the low-fat instructions at both the 10- and 20-week assessment, and 3 of the 13 were compliant with the low-fat instructions at one of the two assessments. Two were fully compliant with the low-fat guidelines, but not the vegan guidelines, and two were noncompliant with both. One patient did not complete the study.

Dr. Bunner reported having no disclosures.

CORRECTED Aug 8: Improvement in pain in the control group, as measured by a visual analogue scale, was misstated in the original story. That value was –2.1.