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Key clinical point: A pro-inflammatory diet characterized by higher dietary inflammatory index (DII) and energy-adjusted DII (E-DII) during adolescence is a significant risk factor for the onset of multiple sclerosis (MS).
Major finding: The risks for MS increased significantly when E-DII was used as a continuous variable (adjusted odds ratio [aOR], 1.53; P = .001) and categorical variable (fourth vs. first quartile: aOR, 7.01; P less than .001). A similar pattern was seen for DII as both continuous and categorical variables.
Study details: This large population-based incident case-control study conducted in Iran included 547 patients with incident MS and 1057 individuals from the general population.
Disclosures: Dr Hébert owns controlling interest in Connecting Health Innovations LLC (CHI), a company planning to license the DII from the University of South Carolina to develop computer and mobile applications. Dr Shivappa is an employee of CHI.
Citation: Abdollahpour I et al. Clin Nutr. 2020 Mar 6. doi: 10.1016/j.clnu.2020.02.033.
Key clinical point: A pro-inflammatory diet characterized by higher dietary inflammatory index (DII) and energy-adjusted DII (E-DII) during adolescence is a significant risk factor for the onset of multiple sclerosis (MS).
Major finding: The risks for MS increased significantly when E-DII was used as a continuous variable (adjusted odds ratio [aOR], 1.53; P = .001) and categorical variable (fourth vs. first quartile: aOR, 7.01; P less than .001). A similar pattern was seen for DII as both continuous and categorical variables.
Study details: This large population-based incident case-control study conducted in Iran included 547 patients with incident MS and 1057 individuals from the general population.
Disclosures: Dr Hébert owns controlling interest in Connecting Health Innovations LLC (CHI), a company planning to license the DII from the University of South Carolina to develop computer and mobile applications. Dr Shivappa is an employee of CHI.
Citation: Abdollahpour I et al. Clin Nutr. 2020 Mar 6. doi: 10.1016/j.clnu.2020.02.033.
Key clinical point: A pro-inflammatory diet characterized by higher dietary inflammatory index (DII) and energy-adjusted DII (E-DII) during adolescence is a significant risk factor for the onset of multiple sclerosis (MS).
Major finding: The risks for MS increased significantly when E-DII was used as a continuous variable (adjusted odds ratio [aOR], 1.53; P = .001) and categorical variable (fourth vs. first quartile: aOR, 7.01; P less than .001). A similar pattern was seen for DII as both continuous and categorical variables.
Study details: This large population-based incident case-control study conducted in Iran included 547 patients with incident MS and 1057 individuals from the general population.
Disclosures: Dr Hébert owns controlling interest in Connecting Health Innovations LLC (CHI), a company planning to license the DII from the University of South Carolina to develop computer and mobile applications. Dr Shivappa is an employee of CHI.
Citation: Abdollahpour I et al. Clin Nutr. 2020 Mar 6. doi: 10.1016/j.clnu.2020.02.033.