Article Type
Changed
Thu, 10/17/2019 - 10:03
Display Headline
Baseline Neurofilament Light Levels Track With Brain Volume Loss in MS

Key clinical point: Baseline levels of the neuropeptide neurofilament light (NfL) correlated with changes in brain volume at the 5- and 10-year marks in patients with multiple sclerosis.

Major finding: At 10 years, the correlation coefficient between baseline NfL and brain volume loss was –0.395 (P = 0.42).

Study details: Prospective cohort study that obtained baseline cerebrospinal fluid NfL levels and sequential brain MRIs in 44 patients with multiple sclerosis.

Disclosures: Dr. Bhan reported receiving research funding from Novartis Norway; two coauthors reported financial relationships with several pharmaceutical companies.

Citation: Bhan A et al. ECTRIMS 2019, Abstract P592.

Publications
Topics
Sections

Key clinical point: Baseline levels of the neuropeptide neurofilament light (NfL) correlated with changes in brain volume at the 5- and 10-year marks in patients with multiple sclerosis.

Major finding: At 10 years, the correlation coefficient between baseline NfL and brain volume loss was –0.395 (P = 0.42).

Study details: Prospective cohort study that obtained baseline cerebrospinal fluid NfL levels and sequential brain MRIs in 44 patients with multiple sclerosis.

Disclosures: Dr. Bhan reported receiving research funding from Novartis Norway; two coauthors reported financial relationships with several pharmaceutical companies.

Citation: Bhan A et al. ECTRIMS 2019, Abstract P592.

Key clinical point: Baseline levels of the neuropeptide neurofilament light (NfL) correlated with changes in brain volume at the 5- and 10-year marks in patients with multiple sclerosis.

Major finding: At 10 years, the correlation coefficient between baseline NfL and brain volume loss was –0.395 (P = 0.42).

Study details: Prospective cohort study that obtained baseline cerebrospinal fluid NfL levels and sequential brain MRIs in 44 patients with multiple sclerosis.

Disclosures: Dr. Bhan reported receiving research funding from Novartis Norway; two coauthors reported financial relationships with several pharmaceutical companies.

Citation: Bhan A et al. ECTRIMS 2019, Abstract P592.

Publications
Publications
Topics
Article Type
Display Headline
Baseline Neurofilament Light Levels Track With Brain Volume Loss in MS
Display Headline
Baseline Neurofilament Light Levels Track With Brain Volume Loss in MS
Sections
Disallow All Ads
Content Gating
No Gating (article Unlocked/Free)
Alternative CME
Disqus Comments
Default
Gate On Date
Tue, 01/29/2019 - 15:45
Un-Gate On Date
Tue, 01/29/2019 - 15:45
Use ProPublica
CFC Schedule Remove Status
Tue, 01/29/2019 - 15:45
Hide sidebar & use full width
render the right sidebar.